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Dysregulation of UDP-glucuronosyltransferases in CCl4 induced liver injury rats.
Xu L, Zheng R, Xie P, Guo Q, Ji H, Li T. Xu L, et al. Among authors: ji h. Chem Biol Interact. 2020 Jul 1;325:109115. doi: 10.1016/j.cbi.2020.109115. Epub 2020 May 4. Chem Biol Interact. 2020. PMID: 32380060
UDP-glucuronosyltransferases (UGTs) are a family of phase II drug metabolizing enzymes that catalyze glucuronidation of numerous endogenous and exogenous substrates. ...
UDP-glucuronosyltransferases (UGTs) are a family of phase II drug metabolizing enzymes that catalyze glucuronidation of numerous endo …
NZ suppresses TLR4/NF-κB signalings and NLRP3 inflammasome activation in LPS-induced RAW264.7 macrophages.
Xiang P, Chen T, Mou Y, Wu H, Xie P, Lu G, Gong X, Hu Q, Zhang Y, Ji H. Xiang P, et al. Among authors: ji h. Inflamm Res. 2015 Oct;64(10):799-808. doi: 10.1007/s00011-015-0863-4. Epub 2015 Aug 23. Inflamm Res. 2015. PMID: 26298161
In addition, NZ markedly inhibited the up-regulation of toll-like receptor 4 (TLR4), myeloid differentiation factor 88 (MyD88) and the activation of nuclear factor kappa B (NF-kappaB) in LPS-stimulated RAW 264.7 macrophages. ...
In addition, NZ markedly inhibited the up-regulation of toll-like receptor 4 (TLR4), myeloid differentiation factor 88 (MyD88) and the activ …
8e Protects against Acute Cerebral Ischemia by Inhibition of PI3Kγ-Mediated Superoxide Generation in Microglia.
Wang L, Wang X, Li T, Zhang Y, Ji H. Wang L, et al. Among authors: ji h. Molecules. 2018 Oct 31;23(11):2828. doi: 10.3390/molecules23112828. Molecules. 2018. PMID: 30384445 Free PMC article.
The aim of this study was to evaluate the efficacy of 8e, a hydrogen sulfide (H2S) releasing derivative of 3-n-butylphthalide (NBP), on brain damage and PI3Kgamma signaling following cerebral ischemia injury. 8e significantly reduced sensorimotor deficits, focal infarction, brain …
The aim of this study was to evaluate the efficacy of 8e, a hydrogen sulfide (H2S) releasing derivative of 3-n-butylphthalide (NBP), on brai …
Ursolic acid promotes the neuroprotection by activating Nrf2 pathway after cerebral ischemia in mice.
Li L, Zhang X, Cui L, Wang L, Liu H, Ji H, Du Y. Li L, et al. Among authors: ji h. Brain Res. 2013 Feb 25;1497:32-9. doi: 10.1016/j.brainres.2012.12.032. Epub 2012 Dec 28. Brain Res. 2013. PMID: 23276496
BACKGROUND: Oxidative and inflammatory damages have been suggested to play an important role in cerebral ischemic pathogenesis, and provide promising therapeutic strategies for stroke. Nuclear factor-erythroid 2-related factor 2 (Nrf2), a pleiotropic transcription factor, …
BACKGROUND: Oxidative and inflammatory damages have been suggested to play an important role in cerebral ischemic pathogenesis, and provide …
Emodinol ameliorates urate nephropathy by regulating renal organic ion transporters and inhibiting immune inflammatory responses in rats.
Wu H, Zhou M, Lu G, Yang Z, Ji H, Hu Q. Wu H, et al. Among authors: ji h. Biomed Pharmacother. 2017 Dec;96:727-735. doi: 10.1016/j.biopha.2017.10.051. Epub 2017 Nov 6. Biomed Pharmacother. 2017. PMID: 29045935
Renal protein expressions of organic ion transporters, components of NLR pyrin domain containing 3 (NLRP3) inflammasome, as well as key factors involved in toll-like receptors (TLRs)/myeloid differentiation factor 88 (MyD88)/nuclear factor kappa B (NF-kappaB) signaling pat …
Renal protein expressions of organic ion transporters, components of NLR pyrin domain containing 3 (NLRP3) inflammasome, as well as key fact …