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Year Number of Results
2015 2
2016 2
2017 2
2018 3
2019 3
2020 3
2021 7
2022 3
2023 2
2024 1

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21 results

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Page 1
Laparoscopic versus open pancreatoduodenectomy for pancreatic or periampullary tumours (LEOPARD-2): a multicentre, patient-blinded, randomised controlled phase 2/3 trial.
van Hilst J, de Rooij T, Bosscha K, Brinkman DJ, van Dieren S, Dijkgraaf MG, Gerhards MF, de Hingh IH, Karsten TM, Lips DJ, Luyer MD, Busch OR, Festen S, Besselink MG; Dutch Pancreatic Cancer Group. van Hilst J, et al. Lancet Gastroenterol Hepatol. 2019 Mar;4(3):199-207. doi: 10.1016/S2468-1253(19)30004-4. Epub 2019 Jan 24. Lancet Gastroenterol Hepatol. 2019. PMID: 30685489 Clinical Trial.
After randomisation of 105 patients (combining patients from both phase 2 and phase 3), of whom 99 underwent surgery, the trial was prematurely terminated by the data and safety monitoring board because of a difference in 90-day complication-related mortality (five [10%] of 50 pa …
After randomisation of 105 patients (combining patients from both phase 2 and phase 3), of whom 99 underwent surgery, the trial was prematur …
The association between viral load and concurrent human papillomavirus infection at the genital and anal sites of young women and the impact of vaccination.
van Eer K, Laâbi I, van Benthem BHB, Steenbergen RDM, King AJ; Medical Microbiological Laboratories and the Public Health Services: Medical Microbiological Laboratories: Certe; ETZ Hospital Tilburg: A. Buiting; Erasmus Medical Center; University Medical Center Utrecht; Public Health Laboratory Amsterdam; Maastricht University Medical Center; Jeroen Bosch Hospital; Radboud University Medical Center; LabMicTA; Medical Laboratory dr. Stein and Collegae; Canisius Wilhelmina Hospital; Public Health Services: PHS Drenthe; PHS IJsselland; PHS Gelderland-Zuid; University Medical Center Utrecht; PHS Rotterdam-Rijnmond; PHS Groningen; PHS Zuid Limburg; PHS Fryslân; PHS Twente; PHS Hart voor Brabant; PHS Amsterdam; PHS Gelderland-Midden. van Eer K, et al. Tumour Virus Res. 2022 Jun;13:200233. doi: 10.1016/j.tvr.2021.200233. Epub 2021 Dec 25. Tumour Virus Res. 2022. PMID: 34958987 Free PMC article.

Concurrent genital-anal HPV often had significantly higher genital viral load (0.09-371 c/cell) than genital-only HPV (3.17E-04-15.9 c/cell, p < 0.0001 to p < 0.05). Moreover, nearly all concurrent genital-anal HPV types had higher genital copy numbers per PCR

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Concurrent genital-anal HPV often had significantly higher genital viral load (0.09-371 c/cell) than genital-only HPV (3.17E-04-15.9 c/cell, …
Risk of diabetes after para-aortic radiation for testicular cancer.
Groot HJ, Gietema JA, Aleman BMP, Incrocci L, de Wit R, Witjes JA, Groenewegen G, de Brouwer P, Meijer OWM, Hulshof MCCM, van den Berg HA, Smilde TJ, Vanneste BGL, Aarts MJ, van den Bergh ACM, Kerst JM, van den Belt-Dusebout AW, Lubberts S, Jóźwiak K, Horenblas S, van Leeuwen FE, Schaapveld M. Groot HJ, et al. Among authors: van leeuwen fe. Br J Cancer. 2018 Oct;119(7):901-907. doi: 10.1038/s41416-018-0248-x. Epub 2018 Oct 9. Br J Cancer. 2018. PMID: 30297773 Free PMC article.
The excess hazard increased with 0.31 with every 10 Gy increase in the prescribed radiation dose (95% CI: 0.11-0.51, P = 0.003, adjusted for age and BMI); restricted to irradiated patients the excess hazard increased with 0.33 (95% CI: -0.14 to 0.81, P = 0.169) with …
The excess hazard increased with 0.31 with every 10 Gy increase in the prescribed radiation dose (95% CI: 0.11-0.51, P = 0.003, adjus …
Platinum exposure and cause-specific mortality among patients with testicular cancer.
Groot HJ, van Leeuwen FE, Lubberts S, Horenblas S, de Wit R, Witjes JA, Groenewegen G, Poortmans PM, Hulshof MCCM, Meijer OWM, de Jong IJ, van den Berg HA, Smilde TJ, Vanneste BGL, Aarts MJB, Jóźwiak K, van den Belt-Dusebout AW, Gietema JA, Schaapveld M. Groot HJ, et al. Among authors: van leeuwen fe. Cancer. 2020 Feb 1;126(3):628-639. doi: 10.1002/cncr.32538. Epub 2019 Nov 15. Cancer. 2020. PMID: 31730712 Free PMC article.

The HR for SMN mortality increased 0.29 (95% CI, 0.19-0.39) per 100 mg/m(2) platinum dose administered (P(trend) < .001). IHD mortality was increased 2.1-fold (95% CI, 1.5-4.2) after platinum-containing chemotherapy in comparison with patients without platinum exposure.

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The HR for SMN mortality increased 0.29 (95% CI, 0.19-0.39) per 100 mg/m(2) platinum dose administered (P(trend) < .001). IHD mort

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Life-prolonging treatment restrictions and outcomes in patients with cancer and COVID-19: an update from the Dutch Oncology COVID-19 Consortium.
de Joode K, Tol J, Hamberg P, Cloos M, Kastelijn EA, Borgers JSW, Nuij VJAA, Klaver Y, Herder GJM, Mutsaers PGNJ, Dumoulin DW, Oomen-de Hoop E, van Diemen NGJ, Libourel EJ, Geraedts EJ, Bootsma GP, van der Leest CH, Peerdeman AL, Herbschleb KH, Visser OJ, Bloemendal HJ, van Laarhoven HWM, de Vries EGE, Hendriks LEL, Beerepoot LV, Westgeest HM, van den Berkmortel FWPJ, Haanen JBAG, Dingemans AC, van der Veldt AAM; DOCC investigators. de Joode K, et al. Eur J Cancer. 2022 Jan;160:261-272. doi: 10.1016/j.ejca.2021.10.009. Epub 2021 Oct 25. Eur J Cancer. 2022. PMID: 34799210 Free PMC article.
Superiority of Step-up Approach vs Open Necrosectomy in Long-term Follow-up of Patients With Necrotizing Pancreatitis.
Hollemans RA, Bakker OJ, Boermeester MA, Bollen TL, Bosscha K, Bruno MJ, Buskens E, Dejong CH, van Duijvendijk P, van Eijck CH, Fockens P, van Goor H, van Grevenstein WM, van der Harst E, Heisterkamp J, Hesselink EJ, Hofker S, Houdijk AP, Karsten T, Kruyt PM, van Laarhoven CJ, Laméris JS, van Leeuwen MS, Manusama ER, Molenaar IQ, Nieuwenhuijs VB, van Ramshorst B, Roos D, Rosman C, Schaapherder AF, van der Schelling GP, Timmer R, Verdonk RC, de Wit RJ, Gooszen HG, Besselink MG, van Santvoort HC; Dutch Pancreatitis Study Group. Hollemans RA, et al. Among authors: van leeuwen ms. Gastroenterology. 2019 Mar;156(4):1016-1026. doi: 10.1053/j.gastro.2018.10.045. Epub 2018 Nov 2. Gastroenterology. 2019. PMID: 30391468 Clinical Trial.
RESULTS: From index admission to long-term follow-up, 19 patients (44%) died or had major complications in the step-up group compared with 33 patients (73%) in the open-necrosectomy group (P = .005). Significantly lower proportions of patients in the step-up group had inci …
RESULTS: From index admission to long-term follow-up, 19 patients (44%) died or had major complications in the step-up group compared with 3 …
21 results