Jeremy A. Hengst - Search Results

Year	Number of Results
2002	2
2004	1
2007	2
2008	1
2009	2
2010	4
2012	1
2013	1
2014	2
2015	2
2017	1
2020	2
2021	2
2022	2
2023	1
2024	1

1

Development of SKI-349, a dual-targeted inhibitor of sphingosine kinase and microtubule polymerization.

Hengst JA, Hegde S, Paulson RF, Yun JK. Hengst JA, et al. Bioorg Med Chem Lett. 2020 Oct 15;30(20):127453. doi: 10.1016/j.bmcl.2020.127453. Epub 2020 Jul 28. Bioorg Med Chem Lett. 2020. PMID: 32736077 Free PMC article.

2

Sphingosine kinase: a key to solving the 'French Paradox'?

Hengst JA, Yun JK. Hengst JA, et al. Br J Pharmacol. 2012 Jul;166(5):1603-4. doi: 10.1111/j.1476-5381.2012.01898.x. Br J Pharmacol. 2012. PMID: 22335554 Free PMC article.

3

The regulatory roles of ROCK and MRCK kinases in the plasticity of cancer cell migration.

Kale VP, Hengst JA, Desai DH, Amin SG, Yun JK. Kale VP, et al. Among authors: hengst ja. Cancer Lett. 2015 Jun 1;361(2):185-96. doi: 10.1016/j.canlet.2015.03.017. Epub 2015 Mar 18. Cancer Lett. 2015. PMID: 25796438 Review.

4

A novel selective multikinase inhibitor of ROCK and MRCK effectively blocks cancer cell migration and invasion.

Kale VP, Hengst JA, Desai DH, Dick TE, Choe KN, Colledge AL, Takahashi Y, Sung SS, Amin SG, Yun JK. Kale VP, et al. Among authors: hengst ja. Cancer Lett. 2014 Nov 28;354(2):299-310. doi: 10.1016/j.canlet.2014.08.032. Epub 2014 Aug 27. Cancer Lett. 2014. PMID: 25172415 Free PMC article.

5

SKI-178: A Multitargeted Inhibitor of Sphingosine Kinase and Microtubule Dynamics Demonstrating Therapeutic Efficacy in Acute Myeloid Leukemia Models.

Hengst JA, Dick TE, Sharma A, Doi K, Hegde S, Tan SF, Geffert LM, Fox TE, Sharma AK, Desai D, Amin S, Kester M, Loughran TP, Paulson RF, Claxton DF, Wang HG, Yun JK. Hengst JA, et al. Cancer Transl Med. 2017 Jul-Aug;3(4):109-121. doi: 10.4103/ctm.ctm_7_17. Epub 2017 Aug 14. Cancer Transl Med. 2017. PMID: 28890935 Free PMC article.

6

Sphingosine Kinase Inhibition Enhances Dimerization of Calreticulin at the Cell Surface in Mitoxantrone-Induced Immunogenic Cell Death.

Nduwumwami AJ, Hengst JA, Yun JK. Nduwumwami AJ, et al. Among authors: hengst ja. J Pharmacol Exp Ther. 2021 Sep;378(3):300-310. doi: 10.1124/jpet.121.000629. Epub 2021 Jun 22. J Pharmacol Exp Ther. 2021. PMID: 34158403

7

Inhibition of Sphingosine Kinase Activity Enhances Immunogenic Cell Surface Exposure of Calreticulin Induced by the Synthetic Cannabinoid 5-epi-CP-55,940.

Hengst JA, Nduwumwami AJ, Raup-Konsavage WM, Vrana KE, Yun JK. Hengst JA, et al. Cannabis Cannabinoid Res. 2022 Oct;7(5):637-647. doi: 10.1089/can.2021.0100. Epub 2021 Nov 26. Cannabis Cannabinoid Res. 2022. PMID: 34846947 Free PMC article.

8

Regulatory Role of Sphingosine-1-Phosphate and C16:0 Ceramide, in Immunogenic Cell Death of Colon Cancer Cells Induced by Bak/Bax-Activation.

Hengst JA, Nduwumwami AJ, Yun JK. Hengst JA, et al. Cancers (Basel). 2022 Oct 22;14(21):5182. doi: 10.3390/cancers14215182. Cancers (Basel). 2022. PMID: 36358599 Free PMC article.

9

Development of a sphingosine kinase 1 specific small-molecule inhibitor.

Hengst JA, Wang X, Sk UH, Sharma AK, Amin S, Yun JK. Hengst JA, et al. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7498-502. doi: 10.1016/j.bmcl.2010.10.005. Epub 2010 Nov 1. Bioorg Med Chem Lett. 2010. PMID: 21050755

10

Characterization of Anticancer Effects of the Analogs of DJ4, a Novel Selective Inhibitor of ROCK and MRCK Kinases.

Kale VP, Hengst JA, Sharma AK, Golla U, Dovat S, Amin SG, Yun JK, Desai DH. Kale VP, et al. Among authors: hengst ja. Pharmaceuticals (Basel). 2023 Jul 26;16(8):1060. doi: 10.3390/ph16081060. Pharmaceuticals (Basel). 2023. PMID: 37630974 Free PMC article.

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