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MicroRNA-200c restoration reveals a cytokine profile to enhance M1 macrophage polarization in breast cancer.
Williams MM, Christenson JL, O'Neill KI, Hafeez SA, Ihle CL, Spoelstra NS, Slansky JE, Richer JK. Williams MM, et al. NPJ Breast Cancer. 2021 May 27;7(1):64. doi: 10.1038/s41523-021-00273-1. NPJ Breast Cancer. 2021. PMID: 34045467 Free PMC article.
Cytokines upregulated by miR-200c correlated with an epithelial gene signature and M1 macrophage polarization in BC patients and predicted a more favorable overall survival for TNBC patients. Our findings demonstrate that immunogenic cytokines (e.g., GM-CSF) are suppressed …
Cytokines upregulated by miR-200c correlated with an epithelial gene signature and M1 macrophage polarization in BC patients and predicted a …