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Strategies To Design Selective Histone Deacetylase Inhibitors.
Melesina J, Simoben CV, Praetorius L, Bülbül EF, Robaa D, Sippl W. Melesina J, et al. ChemMedChem. 2021 May 6;16(9):1336-1359. doi: 10.1002/cmdc.202000934. Epub 2021 Feb 19. ChemMedChem. 2021. PMID: 33428327 Review.
Current trends in development of HDAC-based chemotherapeutics.
Cheshmazar N, Hamzeh-Mivehroud M, Nozad Charoudeh H, Hemmati S, Melesina J, Dastmalchi S. Cheshmazar N, et al. Among authors: melesina j. Life Sci. 2022 Nov 1;308:120946. doi: 10.1016/j.lfs.2022.120946. Epub 2022 Sep 10. Life Sci. 2022. PMID: 36096240 Review.
Synthesis, biological evaluation, and molecular docking studies of aldotetronic acid-based LpxC inhibitors.
Wimmer S, Hoff K, Martin B, Grewer M, Denni L, Lascorz Massanet R, Raimondi MV, Bülbül EF, Melesina J, Hotop SK, Haupenthal J, Rohde H, Heisig P, Hirsch AKH, Brönstrup M, Sippl W, Holl R. Wimmer S, et al. Among authors: melesina j. Bioorg Chem. 2023 Feb;131:106331. doi: 10.1016/j.bioorg.2022.106331. Epub 2022 Dec 19. Bioorg Chem. 2023. PMID: 36587505
Isoform-selective HDAC1/6/8 inhibitors with an imidazo-ketopiperazine cap containing stereochemical diversity.
Lecointre B, Narozny R, Borrello MT, Senger J, Chakrabarti A, Jung M, Marek M, Romier C, Melesina J, Sippl W, Bischoff L, Ganesan A. Lecointre B, et al. Among authors: melesina j. Philos Trans R Soc Lond B Biol Sci. 2018 Jun 5;373(1748):20170364. doi: 10.1098/rstb.2017.0364. Philos Trans R Soc Lond B Biol Sci. 2018. PMID: 29685969 Free PMC article.
32 results