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Antisense oligonucleotide-mediated disruption of HTT caspase-6 cleavage site ameliorates the phenotype of YAC128 Huntington disease mice.
Kuijper EC, Overzier M, Suidgeest E, Dzyubachyk O, Maguin C, Pérot JB, Flament J, Ariyurek Y, Mei H, Buijsen RAM, van der Weerd L, van Roon-Mom W. Kuijper EC, et al. Among authors: perot jb. Neurobiol Dis. 2024 Jan;190:106368. doi: 10.1016/j.nbd.2023.106368. Epub 2023 Nov 29. Neurobiol Dis. 2024. PMID: 38040383 Free article.
SCA7 Mouse Cerebellar Pathology Reveals Preferential Downregulation of Key Purkinje Cell-Identity Genes and Shared Disease Signature with SCA1 and SCA2.
Niewiadomska-Cimicka A, Doussau F, Perot JB, Roux MJ, Keime C, Hache A, Piguet F, Novati A, Weber C, Yalcin B, Meziane H, Champy MF, Grandgirard E, Karam A, Messaddeq N, Eisenmann A, Brouillet E, Nguyen HHP, Flament J, Isope P, Trottier Y. Niewiadomska-Cimicka A, et al. Among authors: perot jb. J Neurosci. 2021 Jun 2;41(22):4910-4936. doi: 10.1523/JNEUROSCI.1882-20.2021. Epub 2021 Apr 22. J Neurosci. 2021. PMID: 33888607 Free PMC article.