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Targeting Stage-Specific Embryonic Antigen 4 (SSEA-4) in Triple Negative Breast Cancer by CAR T Cells Results in Unexpected on Target/off Tumor Toxicities in Mice.
Pfeifer R, Al Rawashdeh W, Brauner J, Martinez-Osuna M, Lock D, Herbel C, Eckardt D, Assenmacher M, Bosio A, Hardt OT, Johnston ICD. Pfeifer R, et al. Among authors: brauner j. Int J Mol Sci. 2023 May 24;24(11):9184. doi: 10.3390/ijms24119184. Int J Mol Sci. 2023. PMID: 37298141 Free PMC article.
Preclinical Evaluation of Novel Folate Receptor 1-Directed CAR T Cells for Ovarian Cancer.
Daigre J, Martinez-Osuna M, Bethke M, Steiner L, Dittmer V, Krischer K, Bleilevens C, Brauner J, Kopatz J, Grundmann MD, Praveen P, Eckardt D, Bosio A, Herbel C. Daigre J, et al. Among authors: brauner j. Cancers (Basel). 2024 Jan 12;16(2):333. doi: 10.3390/cancers16020333. Cancers (Basel). 2024. PMID: 38254822 Free PMC article.
Identification of CD318, TSPAN8 and CD66c as target candidates for CAR T cell based immunotherapy of pancreatic adenocarcinoma.
Schäfer D, Tomiuk S, Küster LN, Rawashdeh WA, Henze J, Tischler-Höhle G, Agorku DJ, Brauner J, Linnartz C, Lock D, Kaiser A, Herbel C, Eckardt D, Lamorte M, Lenhard D, Schüler J, Ströbel P, Missbach-Guentner J, Pinkert-Leetsch D, Alves F, Bosio A, Hardt O. Schäfer D, et al. Among authors: brauner j. Nat Commun. 2021 Mar 5;12(1):1453. doi: 10.1038/s41467-021-21774-4. Nat Commun. 2021. PMID: 33674603 Free PMC article.