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Page 1
3-hydroxykynurenine is a ROS-inducing cytotoxic tryptophan metabolite that disrupts the TCA cycle.
bioRxiv [Preprint]. 2023 Jul 10:2023.07.10.548411. doi: 10.1101/2023.07.10.548411.
bioRxiv. 2023.
PMID: 37502990
Free PMC article.
Preprint.
Mitochondrial Pyruvate Carrier Function in Health and Disease across the Lifespan.
Buchanan JL, Taylor EB.
Buchanan JL, et al.
Biomolecules. 2020 Aug 8;10(8):1162. doi: 10.3390/biom10081162.
Biomolecules. 2020.
PMID: 32784379
Free PMC article.
Review.
Item in Clipboard
Malic Enzyme 1 Absence in Synovial Sarcoma Shifts Antioxidant System Dependence and Increases Sensitivity to Ferroptosis Induction with ACXT-3102.
Brashears CB, Prudner BC, Rathore R, Caldwell KE, Dehner CA, Buchanan JL, Lange SES, Poulin N, Sehn JK, Roszik J, Spitzer D, Jones KB, O'Keefe R, Nielsen TO, Taylor EB, Held JM, Hawkins W, Van Tine BA.
Brashears CB, et al. Among authors: buchanan jl.
Clin Cancer Res. 2022 Aug 15;28(16):3573-3589. doi: 10.1158/1078-0432.CCR-22-0470.
Clin Cancer Res. 2022.
PMID: 35421237
Free PMC article.
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Isolated Effects of Plasma Freezing versus Thawing on Metabolite Stability.
Buchanan JL, Tormes Vaquerano J, Taylor EB.
Buchanan JL, et al.
Metabolites. 2022 Nov 11;12(11):1098. doi: 10.3390/metabo12111098.
Metabolites. 2022.
PMID: 36422241
Free PMC article.
Item in Clipboard
Disrupting Mitochondrial Pyruvate Uptake Directs Glutamine into the TCA Cycle away from Glutathione Synthesis and Impairs Hepatocellular Tumorigenesis.
Tompkins SC, Sheldon RD, Rauckhorst AJ, Noterman MF, Solst SR, Buchanan JL, Mapuskar KA, Pewa AD, Gray LR, Oonthonpan L, Sharma A, Scerbo DA, Dupuy AJ, Spitz DR, Taylor EB.
Tompkins SC, et al. Among authors: buchanan jl.
Cell Rep. 2019 Sep 3;28(10):2608-2619.e6. doi: 10.1016/j.celrep.2019.07.098.
Cell Rep. 2019.
PMID: 31484072
Free PMC article.
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