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Page 1
Hypericin affects cancer side populations via competitive inhibition of BCRP.
Vargová J, Mikeš J, Jendželovský R, Mikešová L, Kuchárová B, Čulka Ľ, Fedr R, Remšík J, Souček K, Kozubík A, Fedoročko P. Vargová J, et al. Biomed Pharmacother. 2018 Mar;99:511-522. doi: 10.1016/j.biopha.2018.01.074. Epub 2018 Feb 20. Biomed Pharmacother. 2018. PMID: 29665654
In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimers.
Janockova J, Korabecny J, Plsikova J, Babkova K, Konkolova E, Kucerova D, Vargova J, Koval J, Jendzelovsky R, Fedorocko P, Kasparkova J, Brabec V, Rosocha J, Soukup O, Hamulakova S, Kuca K, Kozurkova M. Janockova J, et al. Among authors: vargova j. J Enzyme Inhib Med Chem. 2019 Dec;34(1):877-897. doi: 10.1080/14756366.2019.1593159. J Enzyme Inhib Med Chem. 2019. PMID: 30938202 Free PMC article.
Death Receptor 5 (TNFRSF10B) Is Upregulated and TRAIL Resistance Is Reversed in Hypoxia and Normoxia in Colorectal Cancer Cell Lines after Treatment with Skyrin, the Active Metabolite of Hypericum spp.
Babinčák M, Jendželovský R, Košuth J, Majerník M, Vargová J, Mikulášek K, Zdráhal Z, Fedoročko P. Babinčák M, et al. Among authors: vargova j. Cancers (Basel). 2021 Apr 1;13(7):1646. doi: 10.3390/cancers13071646. Cancers (Basel). 2021. PMID: 33916015 Free PMC article.
Synthesis of New Biscoumarin Derivatives, In Vitro Cholinesterase Inhibition, Molecular Modelling and Antiproliferative Effect in A549 Human Lung Carcinoma Cells.
Hudáčová M, Hamuľaková S, Konkoľová E, Jendželovský R, Vargová J, Ševc J, Fedoročko P, Soukup O, Janočková J, Ihnatova V, Kučera T, Bzonek P, Novakova N, Jun D, Junova L, Korábečný J, Kuča K, Kožurková M. Hudáčová M, et al. Among authors: vargova j. Int J Mol Sci. 2021 Apr 7;22(8):3830. doi: 10.3390/ijms22083830. Int J Mol Sci. 2021. PMID: 33917200 Free PMC article.
Conjunction of glutathione level, NAD(P)H/FAD redox status and hypericin content as a potential factor affecting colon cancer cell resistance to photodynamic therapy with hypericin.
Mikešová L, Mikeš J, Kovaľ J, Gyurászová K, Culka L, Vargová J, Valeková B, Fedoročko P. Mikešová L, et al. Among authors: vargova j. Photodiagnosis Photodyn Ther. 2013 Dec;10(4):470-83. doi: 10.1016/j.pdpdt.2013.04.003. Epub 2013 May 25. Photodiagnosis Photodyn Ther. 2013. PMID: 24284100