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MYT1L haploinsufficiency in human neurons and mice causes autism-associated phenotypes that can be reversed by genetic and pharmacologic intervention.
Mol Psychiatry. 2023 May;28(5):2122-2135. doi: 10.1038/s41380-023-01959-7. Epub 2023 Feb 14.
Mol Psychiatry. 2023.
PMID: 36782060
Free PMC article.
cIAP1/2 antagonism eliminates MHC class I-negative tumors through T cell-dependent reprogramming of mononuclear phagocytes.
Roehle K, Qiang L, Ventre KS, Heid D, Ali LR, Lenehan P, Heckler M, Crowley SJ, Stump CT, Ro G, Godicelj A, Bhuiyan AM, Yang A, Quiles Del Rey M, Biary T, Luoma AM, Bruck PT, Tegethoff JF, Nopper SL, Li J, Byrne KT, Pelletier M, Wucherpfennig KW, Stanger BZ, Akin JJ, Mancias JD, Agudo J, Dougan M, Dougan SK.
Roehle K, et al. Among authors: tegethoff jf.
Sci Transl Med. 2021 May 19;13(594):eabf5058. doi: 10.1126/scitranslmed.abf5058.
Sci Transl Med. 2021.
PMID: 34011631
Free PMC article.
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Application of induced pluripotent stem cell technology for the investigation of hematological disorders.
Dolatshad H, Tatwavedi D, Ahmed D, Tegethoff JF, Boultwood J, Pellagatti A.
Dolatshad H, et al. Among authors: tegethoff jf.
Adv Biol Regul. 2019 Jan;71:19-33. doi: 10.1016/j.jbior.2018.10.001. Epub 2018 Oct 10.
Adv Biol Regul. 2019.
PMID: 30341008
Review.
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Methylisoindigo and Its Bromo-Derivatives Are Selective Tyrosine Kinase Inhibitors, Repressing Cellular Stat3 Activity, and Target CD133+ Cancer Stem Cells in PDAC.
Tegethoff J, Bischoff R, Saleh S, Blagojevic B, Merz KH, Cheng X.
Tegethoff J, et al.
Molecules. 2017 Sep 13;22(9):1546. doi: 10.3390/molecules22091546.
Molecules. 2017.
PMID: 32961646
Free PMC article.
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