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2019 | 3 |
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Page 1
Mitigating RNA Toxicity in Myotonic Dystrophy using Small Molecules.
Int J Mol Sci. 2019 Aug 17;20(16):4017. doi: 10.3390/ijms20164017.
Int J Mol Sci. 2019.
PMID: 31426500
Free PMC article.
Review.
Molecular characterization of myotonic dystrophy fibroblast cell lines for use in small molecule screening.
Jenquin JR, O'Brien AP, Poukalov K, Lu Y, Frias JA, Shorrock HK, Richardson JI, Mazdiyasni H, Yang H, Huigens RW 3rd, Boykin D, Ranum LPW, Cleary JD, Wang ET, Berglund JA.
Jenquin JR, et al.
iScience. 2022 Apr 4;25(5):104198. doi: 10.1016/j.isci.2022.104198. eCollection 2022 May 20.
iScience. 2022.
PMID: 35479399
Free PMC article.
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Furamidine Rescues Myotonic Dystrophy Type I Associated Mis-Splicing through Multiple Mechanisms.
Jenquin JR, Coonrod LA, Silverglate QA, Pellitier NA, Hale MA, Xia G, Nakamori M, Berglund JA.
Jenquin JR, et al.
ACS Chem Biol. 2018 Sep 21;13(9):2708-2718. doi: 10.1021/acschembio.8b00646. Epub 2018 Aug 27.
ACS Chem Biol. 2018.
PMID: 30118588
Free PMC article.
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A CTG repeat-selective chemical screen identifies microtubule inhibitors as selective modulators of toxic CUG RNA levels.
Reddy K, Jenquin JR, McConnell OL, Cleary JD, Richardson JI, Pinto BS, Haerle MC, Delgado E, Planco L, Nakamori M, Wang ET, Berglund JA.
Reddy K, et al. Among authors: jenquin jr.
Proc Natl Acad Sci U S A. 2019 Oct 15;116(42):20991-21000. doi: 10.1073/pnas.1901893116. Epub 2019 Sep 30.
Proc Natl Acad Sci U S A. 2019.
PMID: 31570586
Free PMC article.
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Combination Treatment of Erythromycin and Furamidine Provides Additive and Synergistic Rescue of Mis-Splicing in Myotonic Dystrophy Type 1 Models.
Jenquin JR, Yang H, Huigens RW 3rd, Nakamori M, Berglund JA.
Jenquin JR, et al.
ACS Pharmacol Transl Sci. 2019 Aug 9;2(4):247-263. doi: 10.1021/acsptsci.9b00020. Epub 2019 Jul 17.
ACS Pharmacol Transl Sci. 2019.
PMID: 31485578
Free PMC article.
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