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Showing results for jan ole stage
Your search for Jan-Ole Skage retrieved no results
WEE1 kinase limits CDK activities to safeguard DNA replication and mitotic entry.
Elbæk CR, Petrosius V, Sørensen CS. Elbæk CR, et al. Mutat Res. 2020 Jan-Apr;819-820:111694. doi: 10.1016/j.mrfmmm.2020.111694. Epub 2020 Feb 25. Mutat Res. 2020. PMID: 32120135 Review.
We discuss how its function is modulated throughout different cell-cycle stages and provide an overview of how WEE1 levels are regulated. Furthermore, we outline recent clinical trials targeting WEE1 and elaborate on the mechanisms behind the anticancer efficacy of WEE1 in …
We discuss how its function is modulated throughout different cell-cycle stages and provide an overview of how WEE1 levels are regula …
Connexin 43: A Target for the Treatment of Inflammation in Secondary Complications of the Kidney and Eye in Diabetes.
Cliff CL, Williams BM, Chadjichristos CE, Mouritzen U, Squires PE, Hills CE. Cliff CL, et al. Int J Mol Sci. 2022 Jan 6;23(2):600. doi: 10.3390/ijms23020600. Int J Mol Sci. 2022. PMID: 35054783 Free PMC article. Review.
Of increasing prevalence, diabetes is characterised by elevated blood glucose and chronic inflammation that precedes the onset of multiple secondary complications, including those of the kidney and the eye. As the leading cause of end stage renal disease and blindness in t …
Of increasing prevalence, diabetes is characterised by elevated blood glucose and chronic inflammation that precedes the onset of multiple s …
The Ku70/80 ring in Non-Homologous End-Joining: easy to slip on, hard to remove.
Kragelund BB, Weterings E, Hartmann-Petersen R, Keijzers G. Kragelund BB, et al. Front Biosci (Landmark Ed). 2016 Jan 1;21(3):514-27. doi: 10.2741/4406. Front Biosci (Landmark Ed). 2016. PMID: 26709791 Free article. Review.
Non-homologous end-joining (NHEJ) is an essential DNA double strand break repair pathway during all cell cycle stages. Deficiency in NHEJ factors can lead to accumulation of unrepaired DNA breaks or faulty DNA repair, which may ultimately result in cell death, senescence o …
Non-homologous end-joining (NHEJ) is an essential DNA double strand break repair pathway during all cell cycle stages. Deficiency in …
The African Light Source: history, context and future.
Connell SH, Dollman K, Kamel G, Khan SA, Mitchell E, Mtingwa SK, Newton MC, Ngabonziza P, Nji E, Norris L, Zema M. Connell SH, et al. J Synchrotron Radiat. 2024 Jan 1;31(Pt 1):1-9. doi: 10.1107/S1600577523009682. Epub 2024 Jan 1. J Synchrotron Radiat. 2024. PMID: 38142406 Free PMC article.
The Conceptual Design Report for the AfLS is in its final editing stages. This document specifies the socio-economic and scientific rationales and the technical aspects amongst others. ...
The Conceptual Design Report for the AfLS is in its final editing stages. This document specifies the socio-economic and scientific r …
A Phase 1 study of GDC-0134, a dual leucine zipper kinase inhibitor, in ALS.
Katz JS, Rothstein JD, Cudkowicz ME, Genge A, Oskarsson B, Hains AB, Chen C, Galanter J, Burgess BL, Cho W, Kerchner GA, Yeh FL, Ghosh AS, Cheeti S, Brooks L, Honigberg L, Couch JA, Rothenberg ME, Brunstein F, Sharma KR, van den Berg L, Berry JD, Glass JD. Katz JS, et al. Ann Clin Transl Neurol. 2022 Jan;9(1):50-66. doi: 10.1002/acn3.51491. Epub 2022 Jan 10. Ann Clin Transl Neurol. 2022. PMID: 35014217 Free PMC article. Clinical Trial.
METHODS: The study included placebo-controlled, single and multiple ascending-dose (SAD; MAD) stages, and an open-label safety expansion (OLE) with adaptive dosing for up to 48 weeks. ...GDC-0134 (up to 1200 mg daily) was well tolerated in the SAD and MAD stages …
METHODS: The study included placebo-controlled, single and multiple ascending-dose (SAD; MAD) stages, and an open-label safety expans …
Home-Based Orolingual Exercise Improves the Coordination of Swallowing and Respiration in Early Parkinson Disease: A Quasi-Experimental Before-and-After Exercise Program Study.
Wang CM, Shieh WY, Ho CS, Hu YW, Wu YR. Wang CM, et al. Front Neurol. 2018 Jul 30;9:624. doi: 10.3389/fneur.2018.00624. eCollection 2018. Front Neurol. 2018. PMID: 30104999 Free PMC article.
Materials and Methods: This study had a quasi-experimental before-and-after exercise program design. Twenty six patients with early-stage PD who were aged 62.12 8.52 years completed a 12-week home-based OLE program. ...This OLE program can serve as a home-bas …
Materials and Methods: This study had a quasi-experimental before-and-after exercise program design. Twenty six patients with early-stage …
Unraveling the Genetic Basis of Fertility Restoration for Cytoplasmic Male Sterile Line WNJ01A Originated From Brassica juncea in Brassica napus.
Yang Q, Nong X, Xu J, Huang F, Wang F, Wu J, Zhang C, Liu C. Yang Q, et al. Front Plant Sci. 2021 Aug 31;12:721980. doi: 10.3389/fpls.2021.721980. eCollection 2021. Front Plant Sci. 2021. PMID: 34531887 Free PMC article.
Here, we performed morphological observation, map-based cloning, and transcriptomic analysis of the F(2) population developed by crossing the CMS line WNJ01A with its restorer line Hui01. Paraffin-embedded sections showed that the sporogenous cell stage was the critical po …
Here, we performed morphological observation, map-based cloning, and transcriptomic analysis of the F(2) population developed by crossing th …
Framework for identifying and visualising emotional atmosphere in online learning environments in the COVID-19 Era.
Yan F, Wu N, Iliyasu AM, Kawamoto K, Hirota K. Yan F, et al. Appl Intell (Dordr). 2022;52(8):9406-9422. doi: 10.1007/s10489-021-02916-z. Epub 2022 Jan 6. Appl Intell (Dordr). 2022. PMID: 35013647 Free PMC article.
The proposed apposite OLE (i.e., AOLE) provides an intelligent 3D visualisation of the classroom atmosphere (CA), which could assist instructors adjust and tailor both content and instruction for maximum delivery. Furthermore, individual learner status could be tracked via …
The proposed apposite OLE (i.e., AOLE) provides an intelligent 3D visualisation of the classroom atmosphere (CA), which could assist …
Germin like protein genes exhibit modular expression during salt and drought stress in elite rice cultivars.
Anum J, O'Shea C, Zeeshan Hyder M, Farrukh S, Skriver K, Malik SI, Yasmin T. Anum J, et al. Mol Biol Rep. 2022 Jan;49(1):293-302. doi: 10.1007/s11033-021-06871-3. Epub 2021 Nov 1. Mol Biol Rep. 2022. PMID: 34725746
METHODS AND RESULTS: In this study, transcriptional variation of eight OsGLP genes (OsGLP3-6, OsGLP4-1, OsGLP8-4, OsGLP8-7, OsGLP8-10, OsGLP8-11 and OsGLP8-12) was analyzed in leaves and roots of two economically important Indica rice cultivars, KS282 and Super Basmati, under sal …
METHODS AND RESULTS: In this study, transcriptional variation of eight OsGLP genes (OsGLP3-6, OsGLP4-1, OsGLP8-4, OsGLP8-7, OsGLP8-10, OsGLP …
ERBB2 Copy Number as a Quantitative Biomarker for Real-World Outcomes to Anti-Human Epidermal Growth Factor Receptor 2 Therapy in Advanced Gastroesophageal Adenocarcinoma.
Zhang L, Hamdani O, Gjoerup O, Cho-Phan C, Snider J, Castellanos E, Nimeiri H, Frampton G, Venstrom JM, Oxnard G, Klempner SJ, Schrock AB. Zhang L, et al. JCO Precis Oncol. 2022 Jan;6:e2100330. doi: 10.1200/PO.21.00330. JCO Precis Oncol. 2022. PMID: 35050711 Free PMC article.
Among trastuzumab-treated patients, no significant associations with ERBB2 CN were observed for disease site, age, stage at advanced diagnosis, or most selected coalterations. CONCLUSION: ERBB2amp was detected in 15% of GEA tissue samples, with significant diversity in ERB …
Among trastuzumab-treated patients, no significant associations with ERBB2 CN were observed for disease site, age, stage at advanced …
27 results