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High-dimensionality Data Analysis of Pharmacological Systems Associated with Complex Diseases.
Hendrickx JO, van Gastel J, Leysen H, Martin B, Maudsley S. Hendrickx JO, et al. Pharmacol Rev. 2020 Jan;72(1):191-217. doi: 10.1124/pr.119.017921. Pharmacol Rev. 2020. PMID: 31843941 Review.
Currently some of the most effective appreciation of biologic disease and drug response complexity is achieved using high-dimensionality (H-D) data streams from transcriptomic, proteomic, metabolomics, or epigenomic pipelines. Multiple H-D data sets are now common a …
Currently some of the most effective appreciation of biologic disease and drug response complexity is achieved using high-dimensionality ( …
Shared control of a 16 semiconductor quantum dot crossbar array.
Borsoi F, Hendrickx NW, John V, Meyer M, Motz S, van Riggelen F, Sammak A, de Snoo SL, Scappucci G, Veldhorst M. Borsoi F, et al. Nat Nanotechnol. 2024 Jan;19(1):21-27. doi: 10.1038/s41565-023-01491-3. Epub 2023 Aug 28. Nat Nanotechnol. 2024. PMID: 37640909 Free PMC article.
Safety and Immune Responses Following Anti-PD-1 Monoclonal Antibody Infusions in Healthy Persons With Human Immunodeficiency Virus on Antiretroviral Therapy.
Gay CL, Bosch RJ, McKhann A, Cha R, Morse GD, Wimbish CL, Campbell DM, Moseley KF, Hendrickx S, Messer M, Benson CA, Overton ET, Paccaly A, Jankovic V, Miller E, Tressler R, Li JZ, Kuritzkes DR, Macatangay BJC, Eron JJ, Hardy WD; A5370 Team. Gay CL, et al. Open Forum Infect Dis. 2024 Jan 11;11(3):ofad694. doi: 10.1093/ofid/ofad694. eCollection 2024 Mar. Open Forum Infect Dis. 2024. PMID: 38449916 Free PMC article. Clinical Trial.
ELISA for the measurement of serum and urinary chorionic gonadotropin concentrations in the laboratory macaque.
Munro CJ, Laughlin LS, Illera JC, Dieter J, Hendrickx AG, Lasley BL. Munro CJ, et al. Am J Primatol. 1997;41(4):307-22. doi: 10.1002/(SICI)1098-2345(1997)41:4<307::AID-AJP3>3.0.CO;2-0. Am J Primatol. 1997. PMID: 9093694
Range of the standard curve is 0.002 to 0.5 ng hCG/well, and the least detectable concentration of hCG is 0.0023 +/- 0.0007 ng/well. Pregnancy was detected in early pregnant macaques (M. fascicularis) on 9 (N = 1/16), 10 (N = 1/16), 11 (N = 1/16), 12 (N = 6/16), 13 (N = 1/ …
Range of the standard curve is 0.002 to 0.5 ng hCG/well, and the least detectable concentration of hCG is 0.0023 +/- 0.0007 ng/well. Pregnan …
Functional and morphological development of lymphoid tissues and immune regulatory and effector function in rhesus monkeys: cytokine-secreting cells, immunoglobulin-secreting cells, and CD5(+) B-1 cells appear early in fetal development.
Makori N, Tarantal AF, Lü FX, Rourke T, Marthas ML, McChesney MB, Hendrickx AG, Miller CJ. Makori N, et al. Clin Diagn Lab Immunol. 2003 Jan;10(1):140-53. doi: 10.1128/cdli.10.1.140-153.2003. Clin Diagn Lab Immunol. 2003. PMID: 12522052 Free PMC article.
The spleens of 80- to 145-day-old fetuses contained immunoglobulin M (IgM)-secreting cells, while IgA-, IgG-, interleukin-6-, and gamma interferon-secreting cells were numerous in the spleens and colons. ...
The spleens of 80- to 145-day-old fetuses contained immunoglobulin M (IgM)-secreting cells, while IgA-, IgG-, interleukin-6-, and gam …
Three versus five micrometer chlorinated polysaccharide-based packings in chiral capillary electrochromatography: efficiency and precision evaluation.
Hendrickx A, Klerck KD, Mangelings D, Clincke L, Heyden YV. Hendrickx A, et al. Biomed Chromatogr. 2014 Jan;28(1):168-81. doi: 10.1002/bmc.3071. Epub 2013 Oct 18. Biomed Chromatogr. 2014. PMID: 24307636
This phenomenon was further examined in this study, evaluating Van Deemter curves. Naphthalene and trans-stilbene oxide were analyzed on four 3 m and four 5 m chlorinated polysaccharide-based chiral stationary phases (CSPs) applying voltages ranging from 5 to 30 kV. …
This phenomenon was further examined in this study, evaluating Van Deemter curves. Naphthalene and trans-stilbene oxide were analyzed on fou …
Central nervous system malformations induced by triamcinolone acetonide in nonhuman primates: pathology.
Tarara RP, Cordy DR, Hendrickx AG. Tarara RP, et al. Teratology. 1989 Jan;39(1):75-84. doi: 10.1002/tera.1420390109. Teratology. 1989. PMID: 2718142
Triamcinolone acetonide (TAC) was administered to pregnant macaques (Macaca mulatta [15] and M. radiata [7]) during gestational days (GD) 23 to 41 using various dosing schedules. ...
Triamcinolone acetonide (TAC) was administered to pregnant macaques (Macaca mulatta [15] and M. radiata [7]) during gestational days …
Comparison of the metabolism of cortisol and triamcinolone acetonide in the early, mid, and late gestational age rhesus monkey (Macaca mulatta).
Slikker W Jr, Althaus ZR, Rowland JM, Hendrickx AG, Hill DE. Slikker W Jr, et al. Dev Pharmacol Ther. 1984;7(5):319-33. doi: 10.1159/000457181. Dev Pharmacol Ther. 1984. PMID: 6478986
Trace amounts of 14C-cortisol and 10 mg/kg 3H-TAC (Kenalog) were simultaneously administered i.m. to the maternal animal. Whole 30-day embryos or 61- to 137-day fetal organs, amniotic fluid, and placenta were collected from 0.5 to 24 h after dose administration and …
Trace amounts of 14C-cortisol and 10 mg/kg 3H-TAC (Kenalog) were simultaneously administered i.m. to the maternal animal. Whole 30-da …