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Year Number of Results
2003 1
2004 1
2006 1
2010 1
2011 1
2013 1
2014 1
2017 4
2019 3
2020 1
2024 0

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15 results

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Page 1
The exploration of aza-quinolines as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors with low brain exposure.
Cadilla R, Deaton DN, Do Y, Elkins PA, Ennulat D, Guss JH, Holt J, Jeune MR, King AG, Klapwijk JC, Kramer HF, Kramer NJ, Laffan SB, Masuria PI, McDougal AV, Mortenson PN, Musetti C, Peckham GE, Pietrak BL, Poole C, Price DJ, Rendina AR, Sati G, Saxty G, Shearer BG, Shewchuk LM, Sneddon HF, Stewart EL, Stuart JD, Thomas DN, Thomson SA, Ward P, Wilson JW, Xu T, Youngman MA. Cadilla R, et al. Among authors: klapwijk jc. Bioorg Med Chem. 2020 Dec 1;28(23):115791. doi: 10.1016/j.bmc.2020.115791. Epub 2020 Oct 3. Bioorg Med Chem. 2020. PMID: 33059303
Challenges for inhaled drug discovery and development: Induced alveolar macrophage responses.
Forbes B, O'Lone R, Allen PP, Cahn A, Clarke C, Collinge M, Dailey LA, Donnelly LE, Dybowski J, Hassall D, Hildebrand D, Jones R, Kilgour J, Klapwijk J, Maier CC, McGovern T, Nikula K, Parry JD, Reed MD, Robinson I, Tomlinson L, Wolfreys A. Forbes B, et al. Among authors: klapwijk j. Adv Drug Deliv Rev. 2014 May;71:15-33. doi: 10.1016/j.addr.2014.02.001. Epub 2014 Feb 13. Adv Drug Deliv Rev. 2014. PMID: 24530633 Free article.
Spontaneous cardiomyopathy in young Sprague-Dawley rats: evaluation of biological and environmental variability.
Chanut F, Kimbrough C, Hailey R, Berridge B, Hughes-Earle A, Davies R, Roland K, Stokes A, Casartelli A, York M, Jordan H, Crivellente F, Cristofori P, Thomas H, Klapwijk J, Adler R. Chanut F, et al. Among authors: klapwijk j. Toxicol Pathol. 2013;41(8):1126-36. doi: 10.1177/0192623313478692. Epub 2013 Mar 7. Toxicol Pathol. 2013. PMID: 23475560
Good Laboratory Practice Preclinical Safety Studies for GSK2696273 (MLV Vector-Based Ex Vivo Gene Therapy for Adenosine Deaminase Deficiency Severe Combined Immunodeficiency) in NSG Mice.
Carriglio N, Klapwijk J, Hernandez RJ, Vezzoli M, Chanut F, Lowe R, Draghici E, Nord M, Albertini P, Cristofori P, Richards J, Staton H, Appleby J, Aiuti A, Sauer AV. Carriglio N, et al. Among authors: klapwijk j. Hum Gene Ther Clin Dev. 2017 Mar;28(1):17-27. doi: 10.1089/humc.2016.191. Hum Gene Ther Clin Dev. 2017. PMID: 28319446
1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: identification of a potent Aurora kinase inhibitor with a favorable antitumor kinase inhibition profile.
Fancelli D, Moll J, Varasi M, Bravo R, Artico R, Berta D, Bindi S, Cameron A, Candiani I, Cappella P, Carpinelli P, Croci W, Forte B, Giorgini ML, Klapwijk J, Marsiglio A, Pesenti E, Rocchetti M, Roletto F, Severino D, Soncini C, Storici P, Tonani R, Zugnoni P, Vianello P. Fancelli D, et al. Among authors: klapwijk j. J Med Chem. 2006 Nov 30;49(24):7247-51. doi: 10.1021/jm060897w. J Med Chem. 2006. PMID: 17125279
A Diagnostic Approach for Rodent Progressive Cardiomyopathy and Like Lesions in Toxicology Studies up to 28 Days in the Sprague Dawley Rat (Part 2 of 2).
Hailey JR, Maleeff BE, Thomas HC, Pearse G, Klapwijk JC, Cristofori PG, Berridge B, Kimbrough CL, Parker GA, Morton D, Elmore S, Hardisty JF, Dybdal NO, Rehagen DA, Fikes JD, Lamb M, Biddle K, Buetow BS, Carreira V, Nyska A, Tripathi NK, Workman HC, Bienvenu JG, Brees I, Turk JR, Adler RR. Hailey JR, et al. Among authors: klapwijk jc. Toxicol Pathol. 2017 Dec;45(8):1055-1066. doi: 10.1177/0192623317743948. Toxicol Pathol. 2017. PMID: 29233079
15 results