Subtype-specific roles of phospholipase C-β via differential interactions with PDZ domain proteins.
Kim JK, Lim S, Kim J, Kim S, Kim JH, Ryu SH, Suh PG.
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Adv Enzyme Regul. 2011;51(1):138-51. doi: 10.1016/j.advenzreg.2010.10.004. Epub 2010 Oct 28.
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PMID: 21035486
Review.
Although PLC-beta3 is selectively down-regulated in neuroendocrine tumors, the expression of PLC-beta1 is increased in small cell lung carcinoma (Stalberg et al., 2003; Strassheim et al., 2000). In our hypothetical model, it is most likely that up- and down regulation of c …
Although PLC-beta3 is selectively down-regulated in neuroendocrine tumors, the expression of PLC-beta1 is increased in small cell lung carci …