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A 6-mRNA host response classifier in whole blood predicts outcomes in COVID-19 and other acute viral infections.
Buturovic L, Zheng H, Tang B, Lai K, Kuan WS, Gillett M, Santram R, Shojaei M, Almansa R, Nieto JÁ, Muñoz S, Herrero C, Antonakos N, Koufargyris P, Kontogiorgi M, Damoraki G, Liesenfeld O, Wacker J, Midic U, Luethy R, Rawling D, Remmel M, Coyle S, Liu YE, Rao AM, Dermadi D, Toh J, Jones LM, Donato M, Khatri P, Giamarellos-Bourboulis EJ, Sweeney TE. Buturovic L, et al. Among authors: wacker j. Sci Rep. 2022 Jan 18;12(1):889. doi: 10.1038/s41598-021-04509-9. Sci Rep. 2022. PMID: 35042868 Free PMC article. Clinical Trial.
Evaluation of a Multivalent Transcriptomic Metric for Diagnosing Surgical Sepsis and Estimating Mortality Among Critically Ill Patients.
Brakenridge SC, Chen UI, Loftus T, Ungaro R, Dirain M, Kerr A, Zhong L, Bacher R, Starostik P, Ghita G, Midic U, Darden D, Fenner B, Wacker J, Efron PA, Liesenfeld O, Sweeney TE, Moldawer LL. Brakenridge SC, et al. Among authors: wacker j. JAMA Netw Open. 2022 Jul 1;5(7):e2221520. doi: 10.1001/jamanetworkopen.2022.21520. JAMA Netw Open. 2022. PMID: 35819783 Free PMC article.
A 29-MRNA HOST RESPONSE WHOLE-BLOOD SIGNATURE IMPROVES PREDICTION OF 28-DAY MORTALITY AND 7-DAY INTENSIVE CARE UNIT CARE IN ADULTS PRESENTING TO THE EMERGENCY DEPARTMENT WITH SUSPECTED ACUTE INFECTION AND/OR SEPSIS.
Kostaki A, Wacker JW, Safarika A, Solomonidi N, Katsaros K, Giannikopoulos G, Koutelidakis IM, Hogan CA, Uhle F, Liesenfeld O, Sweeney TE, Giamarellos-Bourboulis EJ. Kostaki A, et al. Among authors: wacker jw. Shock. 2022 Sep 1;58(3):224-230. doi: 10.1097/SHK.0000000000001970. Epub 2022 Aug 26. Shock. 2022. PMID: 36125356 Free PMC article.
A host transcriptomic signature for identification of respiratory viral infections in the community.
Almansa R, Herrero-Rodríguez C, Martínez-Huélamo M, Vicente-Andres MDP, Nieto-Barbero JA, Martín-Ballesteros M, Rodilla-Carvajal MDM, de la Fuente A, Ortega A, Alonso-Ramos MJ, Wacker J, Liesenfeld O, Sweeney TE, Bermejo-Martin JF, García-Ortiz L; PREVISE Study Group. Almansa R, et al. Among authors: wacker j. Eur J Clin Invest. 2021 Dec;51(12):e13626. doi: 10.1111/eci.13626. Epub 2021 Jun 13. Eur J Clin Invest. 2021. PMID: 34120332
Prospective validation of a transcriptomic severity classifier among patients with suspected acute infection and sepsis in the emergency department.
Galtung N, Diehl-Wiesenecker E, Lehmann D, Markmann N, Bergström WH, Wacker J, Liesenfeld O, Mayhew M, Buturovic L, Luethy R, Sweeney TE, Tauber R, Kappert K, Somasundaram R, Bauer W. Galtung N, et al. Among authors: wacker j. Eur J Emerg Med. 2022 Oct 1;29(5):357-365. doi: 10.1097/MEJ.0000000000000931. Epub 2022 Apr 21. Eur J Emerg Med. 2022. PMID: 35467566 Free PMC article.
A 29-mRNA host response test from blood accurately distinguishes bacterial and viral infections among emergency department patients.
Safarika A, Wacker JW, Katsaros K, Solomonidi N, Giannikopoulos G, Kotsaki A, Koutelidakis IM, Coyle SM, Cheng HK, Liesenfeld O, Sweeney TE, Giamarellos-Bourboulis EJ. Safarika A, et al. Among authors: wacker jw. Intensive Care Med Exp. 2021 Jun 18;9(1):31. doi: 10.1186/s40635-021-00394-8. Intensive Care Med Exp. 2021. PMID: 34142256 Free PMC article.
A Novel 29-Messenger RNA Host-Response Assay From Whole Blood Accurately Identifies Bacterial and Viral Infections in Patients Presenting to the Emergency Department With Suspected Infections: A Prospective Observational Study.
Bauer W, Kappert K, Galtung N, Lehmann D, Wacker J, Cheng HK, Liesenfeld O, Buturovic L, Luethy R, Sweeney TE, Tauber R, Somasundaram R. Bauer W, et al. Among authors: wacker j. Crit Care Med. 2021 Oct 1;49(10):1664-1673. doi: 10.1097/CCM.0000000000005119. Crit Care Med. 2021. PMID: 34166284 Free PMC article.
12 results