Jakub Ptacek - Search Results

Year	Number of Results
2014	2
2015	1
2016	2
2018	1
2020	2
2023	4
2024	0

1

Determining Potency of Inhibitors Targeting Histone Deacetylase 6 by Quantification of Acetylated Tubulin in Cells.

Mikesova J, Ondrakova M, Jelinkova I, Ptacek J, Novakova Z, Barinka C. Mikesova J, et al. Among authors: ptacek j. Methods Mol Biol. 2023;2589:455-466. doi: 10.1007/978-1-0716-2788-4_29. Methods Mol Biol. 2023. PMID: 36255642

2

Targeting Prostate Cancer Using Bispecific T-Cell Engagers against Prostate-Specific Membrane Antigen.

Das G, Ptacek J, Havlinova B, Nedvedova J, Barinka C, Novakova Z. Das G, et al. Among authors: ptacek j. ACS Pharmacol Transl Sci. 2023 Oct 6;6(11):1703-1714. doi: 10.1021/acsptsci.3c00159. eCollection 2023 Nov 10. ACS Pharmacol Transl Sci. 2023. PMID: 37974624 Free article.

3

Comprehensive Mechanistic View of the Hydrolysis of Oxadiazole-Based Inhibitors by Histone Deacetylase 6 (HDAC6).

Motlová L, Šnajdr I, Kutil Z, Andris E, Ptáček J, Novotná A, Nováková Z, Havlínová B, Tueckmantel W, Dráberová H, Majer P, Schutkowski M, Kozikowski A, Rulíšek L, Bařinka C. Motlová L, et al. Among authors: ptacek j. ACS Chem Biol. 2023 Jul 21;18(7):1594-1610. doi: 10.1021/acschembio.3c00212. Epub 2023 Jul 1. ACS Chem Biol. 2023. PMID: 37392419 Free PMC article.

4

Selectivity of Hydroxamate- and Difluoromethyloxadiazole-Based Inhibitors of Histone Deacetylase 6 In Vitro and in Cells.

Ptacek J, Snajdr I, Schimer J, Kutil Z, Mikesova J, Baranova P, Havlinova B, Tueckmantel W, Majer P, Kozikowski A, Barinka C. Ptacek J, et al. Int J Mol Sci. 2023 Mar 1;24(5):4720. doi: 10.3390/ijms24054720. Int J Mol Sci. 2023. PMID: 36902164 Free PMC article.

5

Structural basis of prostate-specific membrane antigen recognition by the A9g RNA aptamer.

Ptacek J, Zhang D, Qiu L, Kruspe S, Motlova L, Kolenko P, Novakova Z, Shubham S, Havlinova B, Baranova P, Chen SJ, Zou X, Giangrande P, Barinka C. Ptacek J, et al. Nucleic Acids Res. 2020 Nov 4;48(19):11130-11145. doi: 10.1093/nar/gkaa494. Nucleic Acids Res. 2020. PMID: 32525981 Free PMC article.

6

Structural characterization of P1'-diversified urea-based inhibitors of glutamate carboxypeptidase II.

Pavlicek J, Ptacek J, Cerny J, Byun Y, Skultetyova L, Pomper MG, Lubkowski J, Barinka C. Pavlicek J, et al. Among authors: ptacek j. Bioorg Med Chem Lett. 2014 May 15;24(10):2340-5. doi: 10.1016/j.bmcl.2014.03.066. Epub 2014 Mar 28. Bioorg Med Chem Lett. 2014. PMID: 24731280 Free PMC article.

7

Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models.

Noonepalle S, Shen S, Ptáček J, Tavares MT, Zhang G, Stránský J, Pavlíček J, Ferreira GM, Hadley M, Pelaez G, Bařinka C, Kozikowski AP, Villagra A. Noonepalle S, et al. Among authors: ptacek j. J Med Chem. 2020 Sep 24;63(18):10246-10262. doi: 10.1021/acs.jmedchem.0c00567. Epub 2020 Sep 2. J Med Chem. 2020. PMID: 32815366

8

Selection and characterization of Anticalins targeting human prostate-specific membrane antigen (PSMA).

Barinka C, Ptacek J, Richter A, Novakova Z, Morath V, Skerra A. Barinka C, et al. Among authors: ptacek j. Protein Eng Des Sel. 2016 Mar;29(3):105-15. doi: 10.1093/protein/gzv065. Epub 2016 Jan 21. Protein Eng Des Sel. 2016. PMID: 26802163

9

The calcium-binding site of human glutamate carboxypeptidase II is critical for dimerization, thermal stability, and enzymatic activity.

Ptacek J, Nedvedova J, Navratil M, Havlinova B, Konvalinka J, Barinka C. Ptacek J, et al. Protein Sci. 2018 Sep;27(9):1575-1584. doi: 10.1002/pro.3460. Protein Sci. 2018. PMID: 30168215 Free PMC article.

10

Unprecedented Binding Mode of Hydroxamate-Based Inhibitors of Glutamate Carboxypeptidase II: Structural Characterization and Biological Activity.

Novakova Z, Wozniak K, Jancarik A, Rais R, Wu Y, Pavlicek J, Ferraris D, Havlinova B, Ptacek J, Vavra J, Hin N, Rojas C, Majer P, Slusher BS, Tsukamoto T, Barinka C. Novakova Z, et al. Among authors: ptacek j. J Med Chem. 2016 May 26;59(10):4539-50. doi: 10.1021/acs.jmedchem.5b01806. Epub 2016 Apr 25. J Med Chem. 2016. PMID: 27074627

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