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Page 1
Discovery of a 53BP1 Small Molecule Antagonist Using a Focused DNA-Encoded Library Screen.
Shell DJ, Foley CA, Wang Q, Smith CM, Guduru SKR, Zeng H, Dong A, Norris-Drouin JL, Axtman M, Hardy PB, Gupta G, Halabelian L, Frye SV, James LI, Pearce KH. Shell DJ, et al. Among authors: norris drouin jl. J Med Chem. 2023 Oct 26;66(20):14133-14149. doi: 10.1021/acs.jmedchem.3c01192. Epub 2023 Oct 2. J Med Chem. 2023. PMID: 37782247 Free PMC article.
PROTAC Linkerology Leads to an Optimized Bivalent Chemical Degrader of Polycomb Repressive Complex 2 (PRC2) Components.
Bashore FM, Foley CA, Ong HW, Rectenwald JM, Hanley RP, Norris-Drouin JL, Cholensky SH, Mills CA, Pearce KH, Herring LE, Kireev D, Frye SV, James LI. Bashore FM, et al. Among authors: norris drouin jl. ACS Chem Biol. 2023 Mar 17;18(3):494-507. doi: 10.1021/acschembio.2c00804. Epub 2023 Mar 6. ACS Chem Biol. 2023. PMID: 36877831 Free PMC article.
Identification of Covalent Cyclic Peptide Inhibitors in mRNA Display.
Iskandar SE, Chiou LF, Leisner TM, Shell DJ, Norris-Drouin JL, Vaziri C, Pearce KH, Bowers AA. Iskandar SE, et al. Among authors: norris drouin jl. J Am Chem Soc. 2023 Jul 19;145(28):15065-15070. doi: 10.1021/jacs.3c04833. Epub 2023 Jul 3. J Am Chem Soc. 2023. PMID: 37395736
SETDB1 Triple Tudor Domain Ligand, (R,R)-59, Promotes Methylation of Akt1 in Cells.
Uguen M, Deng Y, Li F, Shell DJ, Norris-Drouin JL, Stashko MA, Ackloo S, Arrowsmith CH, James LI, Liu P, Pearce KH, Frye SV. Uguen M, et al. Among authors: norris drouin jl. ACS Chem Biol. 2023 Aug 18;18(8):1846-1853. doi: 10.1021/acschembio.3c00280. Epub 2023 Aug 9. ACS Chem Biol. 2023. PMID: 37556795 Free PMC article.
SETDB1 Triple Tudor Domain Ligand, ( R,R )-59, Promotes Methylation of Akt1 in Cells.
Uguen M, Deng Y, Li F, Shell DJ, Norris-Drouin JL, Stashko MA, Ackloo S, Arrowsmith CH, James LI, Liu P, Pearce KH, Frye SV. Uguen M, et al. Among authors: norris drouin jl. bioRxiv [Preprint]. 2023 May 10:2023.05.10.539986. doi: 10.1101/2023.05.10.539986. bioRxiv. 2023. PMID: 37214894 Free PMC article. Updated. Preprint.
21 results