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Imatinib inhibits the regrowth of human colon cancer cells after treatment with 5-FU and cooperates with vitamin D analogue PRI-2191 in the downregulation of expression of stemness-related genes in 5-FU refractory cells.
Kotlarz A, Przybyszewska M, Swoboda P, Neska J, Miłoszewska J, Grygorowicz MA, Kutner A, Markowicz S. Kotlarz A, et al. J Steroid Biochem Mol Biol. 2019 May;189:48-62. doi: 10.1016/j.jsbmb.2019.02.003. Epub 2019 Feb 14. J Steroid Biochem Mol Biol. 2019. PMID: 30772447