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Identification of hub genes and potential molecular mechanisms related to radiotherapy sensitivity in rectal cancer based on multiple datasets.
Zhao P, Zhen H, Zhao H, Huang Y, Cao B. Zhao P, et al. J Transl Med. 2023 Mar 6;21(1):176. doi: 10.1186/s12967-023-04029-2. J Transl Med. 2023. PMID: 36879254 Free PMC article.
Based on CIBERSORT algorithm, Genomics of Drug Sensitivity in Cancer (GDSC) database, Gene set variation analysis (GSVA), enrichment analysis (GSEA), nomogram, motif enrichment and non-coding RNA network analyses, the associations between hub genes and immune cell infiltration, d …
Based on CIBERSORT algorithm, Genomics of Drug Sensitivity in Cancer (GDSC) database, Gene set variation analysis (GSVA), enrichment analysi …
Three hematologic/immune system-specific expressed genes are considered as the potential biomarkers for the diagnosis of early rheumatoid arthritis through bioinformatics analysis.
Cheng Q, Chen X, Wu H, Du Y. Cheng Q, et al. J Transl Med. 2021 Jan 6;19(1):18. doi: 10.1186/s12967-020-02689-y. J Transl Med. 2021. PMID: 33407587 Free PMC article.
METHODS: Microarray datasets for synovial tissue in RA or osteoarthritis (OA) were downloaded from the Gene Expression Omnibus (GEO) database, and differentially expressed genes (DEGs) were identified by R software. Tissue/organ-specific genes were recognized by BioGPS. .. …
METHODS: Microarray datasets for synovial tissue in RA or osteoarthritis (OA) were downloaded from the Gene Expression Omnibus (GEO) databas …
Decoding ceRNA regulatory network and autophagy-related genes in benign prostatic hyperplasia.
Zhou L, Li Y, Li J, Yao H, Huang J, Li C, Wang L. Zhou L, et al. Int J Biol Macromol. 2023 Jan 15;225:997-1009. doi: 10.1016/j.ijbiomac.2022.11.162. Epub 2022 Nov 17. Int J Biol Macromol. 2023. PMID: 36403772
Accordingly, we determined the differentially expressed RNAs (DERNAs) between BPH tissues and normal prostate tissues. WebGestalt and R package (clusterprofiler) was used to enrichment analysis. Clinical correlations were analyzed using Spearman's coefficient. TargetScan, …
Accordingly, we determined the differentially expressed RNAs (DERNAs) between BPH tissues and normal prostate tissues. WebGestalt and R …
Bioinformatic Analysis of lncRNA Mediated CeRNA Network in Intestinal Ischemia/Reperfusion Injury.
Zhu L, Yang X, Yao Z, Wang Z, Lai Y, Xu S, Liu K, Zhao B. Zhu L, et al. J Surg Res. 2023 Apr;284:280-289. doi: 10.1016/j.jss.2022.11.063. Epub 2023 Jan 6. J Surg Res. 2023. PMID: 36621258
INTRODUCTION: Recently, accumulating studies have reported the roles of competitive endogenous RNA (ceRNA) networks in ischemia/reperfusion (I/R) injury in several organs, including the liver, kidney, heart, brain, and intestine. ...CONCLUSIONS: The results provide …
INTRODUCTION: Recently, accumulating studies have reported the roles of competitive endogenous RNA (ceRNA) networks in ischemia/reper …
m6A modified BACE1-AS contributes to liver metastasis and stemness-like properties in colorectal cancer through TUFT1 dependent activation of Wnt signaling.
Wang X, Liu Y, Zhou M, Yu L, Si Z. Wang X, et al. J Exp Clin Cancer Res. 2023 Nov 21;42(1):306. doi: 10.1186/s13046-023-02881-0. J Exp Clin Cancer Res. 2023. PMID: 37986103 Free PMC article.
Moreover, BACE1-AS maintains the stemness-like properties of CRC cells. Mechanically, BACE1-AS promoted TUFT1 expression by ceRNA network through miR-214-3p. CRC patients with such ceRNA network suffer poorer prognosis than ceRNA-negative patients. ...
Moreover, BACE1-AS maintains the stemness-like properties of CRC cells. Mechanically, BACE1-AS promoted TUFT1 expression by ceRNA net …
Identification of lncRNA-miRNA-mRNA ceRNA network as biomarkers for acute kidney injury.
Hu C, Li J. Hu C, et al. Am J Transl Res. 2023 Sep 15;15(9):5730-5746. eCollection 2023. Am J Transl Res. 2023. PMID: 37854219 Free PMC article.
The ceRNA regulatory networks, GO and KEGG enrichment analysis, and protein-protein interaction (PPI) of I/R and CIS induced AKI specific genes were constructed. ...The common ceRNA network was constructed between CIS group and I/R induced AKI group, w …
The ceRNA regulatory networks, GO and KEGG enrichment analysis, and protein-protein interaction (PPI) of I/R and CIS induced A …
Integrated Bioinformatics and Validation of lncRNA-Mediated ceRNA Network in Myocardial Ischemia/Reperfusion Injury.
Han Y, Jin G, Pan M, Fang Z, Lu D, Cai W, Xu C. Han Y, et al. J Immunol Res. 2022 Sep 21;2022:7260801. doi: 10.1155/2022/7260801. eCollection 2022. J Immunol Res. 2022. PMID: 36189147 Free PMC article.
This study is aimed at exploring the molecule mechanism of lncRNA-mediated competing endogenous RNA (ceRNA) network in MI/R. METHODS: The dataset profiles of MI/R and normal tissues (GSE130217 and GSE124176) were obtained from the GEO database. ...CONCLUSION: …
This study is aimed at exploring the molecule mechanism of lncRNA-mediated competing endogenous RNA (ceRNA) network in MI/R. M …
210 results