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Year Number of Results
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2014 3
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2023 3
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26 results

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Page 1
Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and a target for cancer immunotherapy.
Logtenberg MEW, Jansen JHM, Raaben M, Toebes M, Franke K, Brandsma AM, Matlung HL, Fauster A, Gomez-Eerland R, Bakker NAM, van der Schot S, Marijt KA, Verdoes M, Haanen JBAG, van den Berg JH, Neefjes J, van den Berg TK, Brummelkamp TR, Leusen JHW, Scheeren FA, Schumacher TN. Logtenberg MEW, et al. Among authors: jansen jhm. Nat Med. 2019 Apr;25(4):612-619. doi: 10.1038/s41591-019-0356-z. Epub 2019 Mar 4. Nat Med. 2019. PMID: 30833751 Free PMC article.
Disruption of the sialic acid/Siglec-9 axis improves antibody-mediated neutrophil cytotoxicity towards tumor cells.
Lustig M, Chan C, Jansen JHM, Bräutigam M, Kölling MA, Gehlert CL, Baumann N, Mester S, Foss S, Andersen JT, Bastian L, Sondermann P, Peipp M, Burger R, Leusen JHW, Valerius T. Lustig M, et al. Among authors: jansen jhm. Front Immunol. 2023 Jun 6;14:1178817. doi: 10.3389/fimmu.2023.1178817. eCollection 2023. Front Immunol. 2023. PMID: 37346044 Free PMC article.
Characterization of human Fc alpha receptor transgenic mice: comparison of CD89 expression and antibody-dependent tumor killing between mouse strains.
Stip MC, Jansen JHM, Nederend M, Tsioumpekou M, Evers M, Olofsen PA, Meyer-Wentrup F, Leusen JHW. Stip MC, et al. Among authors: jansen jhm. Cancer Immunol Immunother. 2023 Sep;72(9):3063-3077. doi: 10.1007/s00262-023-03478-4. Epub 2023 Jun 20. Cancer Immunol Immunother. 2023. PMID: 37338671 Free PMC article.
Immune Effector Functions of Human IgG2 Antibodies against EGFR.
Rösner T, Kahle S, Montenegro F, Matlung HL, Jansen JHM, Evers M, Beurskens F, Leusen JHW, van den Berg TK, Valerius T. Rösner T, et al. Among authors: jansen jhm. Mol Cancer Ther. 2019 Jan;18(1):75-88. doi: 10.1158/1535-7163.MCT-18-0341. Epub 2018 Oct 3. Mol Cancer Ther. 2019. PMID: 30282813
The selection of variable regions affects effector mechanisms of IgA antibodies against CD20.
Evers M, Rösner T, Dünkel A, Jansen JHM, Baumann N, Ten Broeke T, Nederend M, Eichholz K, Klausz K, Reiding K, Schewe DM, Kellner C, Peipp M, Leusen JHW, Valerius T. Evers M, et al. Among authors: jansen jhm. Blood Adv. 2021 Oct 12;5(19):3807-3820. doi: 10.1182/bloodadvances.2021004598. Blood Adv. 2021. PMID: 34525171 Free PMC article.
IgA-Mediated Killing of Tumor Cells by Neutrophils Is Enhanced by CD47-SIRPα Checkpoint Inhibition.
Treffers LW, Ten Broeke T, Rösner T, Jansen JHM, van Houdt M, Kahle S, Schornagel K, Verkuijlen PJJH, Prins JM, Franke K, Kuijpers TW, van den Berg TK, Valerius T, Leusen JHW, Matlung HL. Treffers LW, et al. Among authors: jansen jhm. Cancer Immunol Res. 2020 Jan;8(1):120-130. doi: 10.1158/2326-6066.CIR-19-0144. Epub 2019 Nov 5. Cancer Immunol Res. 2020. PMID: 31690649
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