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Value-assessment of computer-assisted navigation strategies during percutaneous needle placement.
Boekestijn I, Azargoshasb S, van Oosterom MN, Slof LJ, Dibbets-Schneider P, Dankelman J, van Erkel AR, Rietbergen DDD, van Leeuwen FWB. Boekestijn I, et al. Int J Comput Assist Radiol Surg. 2022 Oct;17(10):1775-1785. doi: 10.1007/s11548-022-02719-8. Epub 2022 Aug 7. Int J Comput Assist Radiol Surg. 2022. PMID: 35934773 Free PMC article.
METHODS: Using a custom biopsy phantom, three consecutive exercises were performed by both novices and experts (n = 26). The exercise came in three options: (1) US-guidance, (2) US-guidance with pre-interventional image-registration (US + Reg) and (3) US-guidance with pre- …
METHODS: Using a custom biopsy phantom, three consecutive exercises were performed by both novices and experts (n = 26). The exercise …
Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration.
Wilman HR, Parisinos CA, Atabaki-Pasdar N, Kelly M, Thomas EL, Neubauer S; IMI DIRECT Consortium; Mahajan A, Hingorani AD, Patel RS, Hemingway H, Franks PW, Bell JD, Banerjee R, Yaghootkar H. Wilman HR, et al. J Hepatol. 2019 Sep;71(3):594-602. doi: 10.1016/j.jhep.2019.05.032. Epub 2019 Jun 19. J Hepatol. 2019. PMID: 31226389 Free PMC article.
METHODS: First, we performed a genome-wide association study (GWAS) in 8,289 individuals from UK Biobank, whose liver iron level had been quantified by magnetic resonance imaging, before validating our findings in an independent cohort (n = 1,513 from IMI DIRECT). Second, …
METHODS: First, we performed a genome-wide association study (GWAS) in 8,289 individuals from UK Biobank, whose liver iron level had been qu …
Stomach cancer risk after treatment for hodgkin lymphoma.
Morton LM, Dores GM, Curtis RE, Lynch CF, Stovall M, Hall P, Gilbert ES, Hodgson DC, Storm HH, Johannesen TB, Smith SA, Weathers RE, Andersson M, Fossa SD, Hauptmann M, Holowaty EJ, Joensuu H, Kaijser M, Kleinerman RA, Langmark F, Pukkala E, Vaalavirta L, van den Belt-Dusebout AW, Fraumeni JF Jr, Travis LB, Aleman BM, van Leeuwen FE. Morton LM, et al. J Clin Oncol. 2013 Sep 20;31(27):3369-77. doi: 10.1200/JCO.2013.50.6832. Epub 2013 Aug 26. J Clin Oncol. 2013. PMID: 23980092 Free PMC article.
Hybrid Tracers Based on Cyanine Backbones Targeting Prostate-Specific Membrane Antigen: Tuning Pharmacokinetic Properties and Exploring Dye-Protein Interaction.
Hensbergen AW, Buckle T, van Willigen DM, Schottelius M, Welling MM, van der Wijk FA, Maurer T, van der Poel HG, van der Pluijm G, van Weerden WM, Wester HJ, van Leeuwen FWB. Hensbergen AW, et al. J Nucl Med. 2020 Feb;61(2):234-241. doi: 10.2967/jnumed.119.233064. Epub 2019 Sep 3. J Nucl Med. 2020. PMID: 31481575 Free PMC article.
Influence of Cow's Milk and Esomeprazole on the Absorption of Erlotinib: A Randomized, Crossover Pharmacokinetic Study in Lung Cancer Patients.
Veerman GDM, Hussaarts KGAM, Peric R, Oomen-de Hoop E, Landa KD, van der Leest CH, Broerse SD, Rutten HB, Belderbos HNA, Steendam CMJ, Paats MS, Koolen SLW, Dingemans AC, van Gelder T, van Leeuwen RWF, Aerts JGJV, Mathijssen RHJ. Veerman GDM, et al. Clin Pharmacokinet. 2021 Jan;60(1):69-77. doi: 10.1007/s40262-020-00910-1. Clin Pharmacokinet. 2021. PMID: 32557346 Free PMC article. Clinical Trial.
RESULTS: Erlotinib area under the curve from time zero to 24 h (AUC(24)) did not significantly change when administered with milk, compared with water, in both non-PPI users (n = 14; - 3%; 95% confidence interval [CI] - 12 to 8%; p = 0.57) and patients who used esomeprazol …
RESULTS: Erlotinib area under the curve from time zero to 24 h (AUC(24)) did not significantly change when administered with milk, compared …
Scientific activity by medical students: the relationship between academic publishing during medical school and publication careers after graduation.
Waaijer CJF, Ommering BWC, van der Wurff LJ, van Leeuwen TN, Dekker FW; NVMO Special Interest Group on Scientific Education. Waaijer CJF, et al. Perspect Med Educ. 2019 Aug;8(4):223-229. doi: 10.1007/s40037-019-0524-3. Perspect Med Educ. 2019. PMID: 31290118 Free PMC article.
We determined whether medical students in the Netherlands who are involved in research, as measured by publication in international journals before graduation: 1) are more likely to publish, 2) publish a greater number of papers, and 3) have higher citation impact scores after gr …
We determined whether medical students in the Netherlands who are involved in research, as measured by publication in international journals …
The best of both worlds: a hybrid approach for optimal pre- and intraoperative identification of sentinel lymph nodes.
KleinJan GH, van Werkhoven E, van den Berg NS, Karakullukcu MB, Zijlmans HJMAA, van der Hage JA, van de Wiel BA, Buckle T, Klop WMC, Horenblas S, Valdés Olmos RA, van der Poel HG, van Leeuwen FWB. KleinJan GH, et al. Eur J Nucl Med Mol Imaging. 2018 Oct;45(11):1915-1925. doi: 10.1007/s00259-018-4028-x. Epub 2018 Apr 25. Eur J Nucl Med Mol Imaging. 2018. PMID: 29696442 Free PMC article.
As the patients acted as their own control, use of hybrid guidance could be compared to conventional radioguidance and the use of blue dye (n = 300). This was based on reported surgical complications, overall survival, LN recurrence free survival, and false negative rates …
As the patients acted as their own control, use of hybrid guidance could be compared to conventional radioguidance and the use of blue dye ( …
Multimodal Surgical Guidance during Sentinel Node Biopsy for Melanoma: Combined Gamma Tracing and Fluorescence Imaging of the Sentinel Node through Use of the Hybrid Tracer Indocyanine Green-(99m)Tc-Nanocolloid.
van den Berg NS, Brouwer OR, Schaafsma BE, Mathéron HM, Klop WM, Balm AJ, van Tinteren H, Nieweg OE, van Leeuwen FW, Valdés Olmos RA. van den Berg NS, et al. Radiology. 2015 May;275(2):521-9. doi: 10.1148/radiol.14140322. Epub 2014 Dec 17. Radiology. 2015. PMID: 25521776
An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers.
Blein S, Bardel C, Danjean V, McGuffog L, Healey S, Barrowdale D, Lee A, Dennis J, Kuchenbaecker KB, Soucy P, Terry MB, Chung WK, Goldgar DE, Buys SS; Breast Cancer Family Registry; Janavicius R, Tihomirova L, Tung N, Dorfling CM, van Rensburg EJ, Neuhausen SL, Ding YC, Gerdes AM, Ejlertsen B, Nielsen FC, Hansen TV, Osorio A, Benitez J, Conejero RA, Segota E, Weitzel JN, Thelander M, Peterlongo P, Radice P, Pensotti V, Dolcetti R, Bonanni B, Peissel B, Zaffaroni D, Scuvera G, Manoukian S, Varesco L, Capone GL, Papi L, Ottini L, Yannoukakos D, Konstantopoulou I, Garber J, Hamann U, Donaldson A, Brady A, Brewer C, Foo C, Evans DG, Frost D, Eccles D; EMBRACE; Douglas F, Cook J, Adlard J, Barwell J, Walker L, Izatt L, Side LE, Kennedy MJ, Tischkowitz M, Rogers MT, Porteous ME, Morrison PJ, Platte R, Eeles R, Davidson R, Hodgson S, Cole T, Godwin AK, Isaacs C, Claes K, De Leeneer K, Meindl A, Gehrig A, Wappenschmidt B, Sutter C, Engel C, Niederacher D, Steinemann D, Plendl H, Kast K, Rhiem K, Ditsch N, Arnold N, Varon-Mateeva R, Schmutzler RK, Preisler-Adams S, Markov NB, Wang-Gohrke S, de Pauw A, Lefol C, Lasset C, Leroux D, Rouleau E, Damiola F; GEMO Study Collaborators; Dreyfus H, B… See abstract for full author list ➔ Blein S, et al. Breast Cancer Res. 2015 Apr 25;17(1):61. doi: 10.1186/s13058-015-0567-2. Breast Cancer Res. 2015. PMID: 25925750 Free PMC article.