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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1968 1
1970 1
1975 2
1976 1
1977 1
1978 1
1980 2
1981 3
1982 1
1983 1
1984 2
1985 1
1986 1
1987 6
1988 3
1989 7
1990 4
1991 6
1992 15
1993 9
1994 9
1995 7
1996 9
1997 15
1998 10
1999 15
2000 16
2001 10
2002 15
2003 16
2004 16
2005 17
2006 9
2007 11
2008 15
2009 19
2010 13
2011 13
2012 16
2013 16
2014 45
2015 74
2016 81
2017 90
2018 103
2019 114
2020 109
2021 139
2022 138
2023 151
2024 51

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1,265 results

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Page 1
Zuranolone for the Treatment of Adults With Major Depressive Disorder: A Randomized, Placebo-Controlled Phase 3 Trial.
Clayton AH, Lasser R, Parikh SV, Iosifescu DV, Jung J, Kotecha M, Forrestal F, Jonas J, Kanes SJ, Doherty J. Clayton AH, et al. Am J Psychiatry. 2023 Sep 1;180(9):676-684. doi: 10.1176/appi.ajp.20220459. Epub 2023 May 3. Am J Psychiatry. 2023. PMID: 37132201 Clinical Trial.
The primary endpoint was change from baseline in total score on the 17-item Hamilton Depression Rating Scale (HAM-D) at day 15. Safety and tolerability were assessed by incidence of adverse events. ...Compared with patients in the placebo group, patients in the zuranolone …
The primary endpoint was change from baseline in total score on the 17-item Hamilton Depression Rating Scale (HAM-D) at day 15. Safet …
CD1 lipidomes reveal lipid-binding motifs and size-based antigen-display mechanisms.
Huang S, Shahine A, Cheng TY, Chen YL, Ng SW, Balaji GR, Farquhar R, Gras S, Hardman CS, Altman JD, Tahiri N, Minnaard AJ, Ogg GS, Mayfield JA, Rossjohn J, Moody DB. Huang S, et al. Cell. 2023 Oct 12;186(21):4583-4596.e13. doi: 10.1016/j.cell.2023.08.022. Epub 2023 Sep 18. Cell. 2023. PMID: 37725977 Free article.
Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.
Hogg SJ, Motorna O, Cluse LA, Johanson TM, Coughlan HD, Raviram R, Myers RM, Costacurta M, Todorovski I, Pijpers L, Bjelosevic S, Williams T, Huskins SN, Kearney CJ, Devlin JR, Fan Z, Jabbari JS, Martin BP, Fareh M, Kelly MJ, Dupéré-Richer D, Sandow JJ, Feran B, Knight D, Khong T, Spencer A, Harrison SJ, Gregory G, Wickramasinghe VO, Webb AI, Taberlay PC, Bromberg KD, Lai A, Papenfuss AT, Smyth GK, Allan RS, Licht JD, Landau DA, Abdel-Wahab O, Shortt J, Vervoort SJ, Johnstone RW. Hogg SJ, et al. Mol Cell. 2021 May 20;81(10):2183-2200.e13. doi: 10.1016/j.molcel.2021.04.015. Mol Cell. 2021. PMID: 34019788 Free PMC article.
Mesenchymal stromal cell apoptosis is required for their therapeutic function.
Pang SHM, D'Rozario J, Mendonca S, Bhuvan T, Payne NL, Zheng D, Hisana A, Wallis G, Barugahare A, Powell D, Rautela J, Huntington ND, Dewson G, Huang DCS, Gray DHD, Heng TSP. Pang SHM, et al. Nat Commun. 2021 Nov 11;12(1):6495. doi: 10.1038/s41467-021-26834-3. Nat Commun. 2021. PMID: 34764248 Free PMC article.
Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway.
Simpson DS, Pang J, Weir A, Kong IY, Fritsch M, Rashidi M, Cooney JP, Davidson KC, Speir M, Djajawi TM, Hughes S, Mackiewicz L, Dayton M, Anderton H, Doerflinger M, Deng Y, Huang AS, Conos SA, Tye H, Chow SH, Rahman A, Norton RS, Naderer T, Nicholson SE, Burgio G, Man SM, Groom JR, Herold MJ, Hawkins ED, Lawlor KE, Strasser A, Silke J, Pellegrini M, Kashkar H, Feltham R, Vince JE. Simpson DS, et al. Immunity. 2022 Mar 8;55(3):423-441.e9. doi: 10.1016/j.immuni.2022.01.003. Epub 2022 Feb 8. Immunity. 2022. PMID: 35139355 Free PMC article.
Lung Allograft Rejection.
Levine DJ, Hachem RR. Levine DJ, et al. Thorac Surg Clin. 2022 May;32(2):221-229. doi: 10.1016/j.thorsurg.2021.12.003. Thorac Surg Clin. 2022. PMID: 35512940 Review.
Collagen dehydration.
Haverkamp RG, Sizeland KH, Wells HC, Kamma-Lorger C. Haverkamp RG, et al. Int J Biol Macromol. 2022 Sep 1;216:140-147. doi: 10.1016/j.ijbiomac.2022.06.180. Epub 2022 Jul 4. Int J Biol Macromol. 2022. PMID: 35793742 Free article.
Here we show that dehydration of type I collagen fibrils, using 2-propanol, results in a two-stage dehydration process. Initially, the fibrils do not change length, i.e. the D-period remains constant, but shrinkage occurs within the fibrils by an increase in the gap region …
Here we show that dehydration of type I collagen fibrils, using 2-propanol, results in a two-stage dehydration process. Initially, the fibri …
Reviews.
[No authors listed] [No authors listed] New Phytol. 1987 Oct;107(2):479. doi: 10.1111/j.1469-8137.1987.tb00198.x. New Phytol. 1987. PMID: 33873838 Review.
The Anatomy of Wood: Its Diversity and Variability. By K. Wilson and D. J. B. White. The Biology of Symbiosis. By D. C. Smith and A. ...Edited by B. J. Berglund....
The Anatomy of Wood: Its Diversity and Variability. By K. Wilson and D. J. B. White. The Biology of Symbiosis. By D. C. …
Caspase-8-driven apoptotic and pyroptotic crosstalk causes cell death and IL-1β release in X-linked inhibitor of apoptosis (XIAP) deficiency.
Hughes SA, Lin M, Weir A, Huang B, Xiong L, Chua NK, Pang J, Santavanond JP, Tixeira R, Doerflinger M, Deng Y, Yu CH, Silke N, Conos SA, Frank D, Simpson DS, Murphy JM, Lawlor KE, Pearson JS, Silke J, Pellegrini M, Herold MJ, Poon IKH, Masters SL, Li M, Tang Q, Zhang Y, Rashidi M, Geng L, Vince JE. Hughes SA, et al. EMBO J. 2023 Mar 1;42(5):e110468. doi: 10.15252/embj.2021110468. Epub 2023 Jan 17. EMBO J. 2023. PMID: 36647737 Free PMC article.
Here, we report that two patients with XIAP deficiency-associated inflammatory bowel disease display increased inflammatory IL-1beta maturation as well as cell death-associated caspase-8 and Gasdermin D (GSDMD) processing in diseased tissue, which is reduced upon patient t …
Here, we report that two patients with XIAP deficiency-associated inflammatory bowel disease display increased inflammatory IL-1beta maturat …
1,265 results