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Page 1
Showing results for vivo comet
Search for Ivo Romet instead (1 results)
Measuring DNA modifications with the comet assay: a compendium of protocols.
Collins A, Møller P, Gajski G, Vodenková S, Abdulwahed A, Anderson D, Bankoglu EE, Bonassi S, Boutet-Robinet E, Brunborg G, Chao C, Cooke MS, Costa C, Costa S, Dhawan A, de Lapuente J, Bo' CD, Dubus J, Dusinska M, Duthie SJ, Yamani NE, Engelward B, Gaivão I, Giovannelli L, Godschalk R, Guilherme S, Gutzkow KB, Habas K, Hernández A, Herrero O, Isidori M, Jha AN, Knasmüller S, Kooter IM, Koppen G, Kruszewski M, Ladeira C, Laffon B, Larramendy M, Hégarat LL, Lewies A, Lewinska A, Liwszyc GE, de Cerain AL, Manjanatha M, Marcos R, Milić M, de Andrade VM, Moretti M, Muruzabal D, Novak M, Oliveira R, Olsen AK, Owiti N, Pacheco M, Pandey AK, Pfuhler S, Pourrut B, Reisinger K, Rojas E, Rundén-Pran E, Sanz-Serrano J, Shaposhnikov S, Sipinen V, Smeets K, Stopper H, Teixeira JP, Valdiglesias V, Valverde M, van Acker F, van Schooten FJ, Vasquez M, Wentzel JF, Wnuk M, Wouters A, Žegura B, Zikmund T, Langie SAS, Azqueta A. Collins A, et al. Nat Protoc. 2023 Mar;18(3):929-989. doi: 10.1038/s41596-022-00754-y. Epub 2023 Jan 27. Nat Protoc. 2023. PMID: 36707722 Free PMC article. Review.
The comet assay is a versatile method to detect nuclear DNA damage in individual eukaryotic cells, from yeast to human. ...Various applications of the comet assay have been validated by research groups in academia, industry and regulatory agencies, and …
The comet assay is a versatile method to detect nuclear DNA damage in individual eukaryotic cells, from yeast to human. ...Var …
Comet assay as a suitable biomarker for in vivo oral carcinogenesis: a systematic review.
Guedes Pinto T, de Souza DV, da Silva GN, Salvadori DMF, Martins MD, Ribeiro DA. Guedes Pinto T, et al. Biomarkers. 2023 Dec;28(8):692-702. doi: 10.1080/1354750X.2023.2298182. Epub 2024 Jan 22. Biomarkers. 2023. PMID: 38131287 Review.
BACKGROUND AND OBJECTIVES: In order to detect genetic damage, different methods have been developed, such as micronuclei and comet assay. The comet assay presents some advantages when compared to the other aforementioned methods, including wide versati …
BACKGROUND AND OBJECTIVES: In order to detect genetic damage, different methods have been developed, such as micronuclei and comet …
The in vivo comet assay: use and status in genotoxicity testing.
Brendler-Schwaab S, Hartmann A, Pfuhler S, Speit G. Brendler-Schwaab S, et al. Mutagenesis. 2005 Jul;20(4):245-54. doi: 10.1093/mutage/gei033. Epub 2005 May 17. Mutagenesis. 2005. PMID: 15899933 Review.
Examples for practical applications of the in vivo comet assay and potential consequences of positive and negative test results are given. ...In accordance with international guidelines for genotoxicity testing the in vivo comet assay is …
Examples for practical applications of the in vivo comet assay and potential consequences of positive and negative test …
The Comet Assay: Assessment of In Vitro and In Vivo DNA Damage.
Bajpayee M, Kumar A, Dhawan A. Bajpayee M, et al. Methods Mol Biol. 2019;2031:237-257. doi: 10.1007/978-1-4939-9646-9_12. Methods Mol Biol. 2019. PMID: 31473963
The recommendations from the international workshops held for the Comet assay have resulted in establishment of guidelines, and the OECD has adopted a guideline for the in vivo Comet assay as a test for assessing DNA damage in animals. ...This c …
The recommendations from the international workshops held for the Comet assay have resulted in establishment of guidelines, an …
The role of the enzyme-modified comet assay in in vivo studies.
Collins A, Vettorazzi A, Azqueta A. Collins A, et al. Toxicol Lett. 2020 Jul 1;327:58-68. doi: 10.1016/j.toxlet.2020.03.016. Epub 2020 Apr 2. Toxicol Lett. 2020. PMID: 32247831
The in vivo comet assay is an established genotoxicity test, with an OECD test guideline, but in its standard form it measures only DNA strand breaks. ...Compounds such as methyl methanesulfonate (MMS) or ethyl methanesulfonate (EMS) could be used as positive …
The in vivo comet assay is an established genotoxicity test, with an OECD test guideline, but in its standard form it m …
The in vitro and in vivo comet assays.
Burlinson B. Burlinson B. Methods Mol Biol. 2012;817:143-63. doi: 10.1007/978-1-61779-421-6_8. Methods Mol Biol. 2012. PMID: 22147572
However, there are instances when these assays alone are inadequate and further testing is required, especially in vivo. Historically, the preferred second assay has been the rodent liver unscheduled DNA synthesis assay but recently this has been superseded b …
However, there are instances when these assays alone are inadequate and further testing is required, especially in vivo. Historically …
The comet assay: ready for 30 more years.
Møller P. Møller P. Mutagenesis. 2018 Feb 24;33(1):1-7. doi: 10.1093/mutage/gex046. Mutagenesis. 2018. PMID: 29325088 Review.
A landmark achievement was reached in 2016 when the Organization for Economic Co-operation and Development adopted a comet assay guideline for in vivo testing of DNA strand breaks in animals. However, the comet assay has much more to offer than …
A landmark achievement was reached in 2016 when the Organization for Economic Co-operation and Development adopted a comet assay …
Experiences with the in vivo and in vitro comet assay in regulatory testing.
Frötschl R. Frötschl R. Mutagenesis. 2015 Jan;30(1):51-7. doi: 10.1093/mutage/geu069. Mutagenesis. 2015. PMID: 25527728
The in vivo comet assay has recently been implemented into regulatory genotoxicity testing of pharmaceuticals with inclusion into the ICH S2R1 guidance. ...The test recommended as second in vivo test is the comet assay in rat liver. The i …
The in vivo comet assay has recently been implemented into regulatory genotoxicity testing of pharmaceuticals with incl …
2,456 results