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Did you mean iveta mrazova (5 results)?
The anticancer drug ellipticine activated with cytochrome P450 mediates DNA damage determining its pharmacological efficiencies: studies with rats, Hepatic Cytochrome P450 Reductase Null (HRN™) mice and pure enzymes.
Stiborová M, Černá V, Moserová M, Mrízová I, Arlt VM, Frei E. Stiborová M, et al. Among authors: mrizova i. Int J Mol Sci. 2014 Dec 25;16(1):284-306. doi: 10.3390/ijms16010284. Int J Mol Sci. 2014. PMID: 25547492 Free PMC article. Review.
Application of hepatic cytochrome b5/P450 reductase null (HBRN) mice to study the role of cytochrome b5 in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine.
Reed L, Indra R, Mrizova I, Moserova M, Schmeiser HH, Wolf CR, Henderson CJ, Stiborova M, Phillips DH, Arlt VM. Reed L, et al. Among authors: mrizova i. Toxicol Appl Pharmacol. 2019 Mar 1;366:64-74. doi: 10.1016/j.taap.2019.01.020. Epub 2019 Jan 25. Toxicol Appl Pharmacol. 2019. PMID: 30685480 Free PMC article.
The impact of chemotherapeutic drugs on the CYP1A1-catalysed metabolism of the environmental carcinogen benzo[a]pyrene: Effects in human colorectal HCT116 TP53(+/+), TP53(+/-) and TP53(-/-) cells.
Willis AJ, Indra R, Wohak LE, Sozeri O, Feser K, Mrizova I, Phillips DH, Stiborova M, Arlt VM. Willis AJ, et al. Among authors: mrizova i. Toxicology. 2018 Apr 1;398-399:1-12. doi: 10.1016/j.tox.2018.02.006. Epub 2018 Feb 19. Toxicology. 2018. PMID: 29471073 Free PMC article.
Impact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3-nitrobenzanthrone.
Arlt VM, Meinl W, Florian S, Nagy E, Barta F, Thomann M, Mrizova I, Krais AM, Liu M, Richards M, Mirza A, Kopka K, Phillips DH, Glatt H, Stiborova M, Schmeiser HH. Arlt VM, et al. Among authors: mrizova i. Arch Toxicol. 2017 Apr;91(4):1957-1975. doi: 10.1007/s00204-016-1808-6. Epub 2016 Aug 24. Arch Toxicol. 2017. PMID: 27557898 Free PMC article.
Pulmonary Inflammation Impacts on CYP1A1-Mediated Respiratory Tract DNA Damage Induced by the Carcinogenic Air Pollutant Benzo[a]pyrene.
Arlt VM, Krais AM, Godschalk RW, Riffo-Vasquez Y, Mrizova I, Roufosse CA, Corbin C, Shi Q, Frei E, Stiborova M, van Schooten FJ, Phillips DH, Spina D. Arlt VM, et al. Among authors: mrizova i. Toxicol Sci. 2015 Aug;146(2):213-25. doi: 10.1093/toxsci/kfv086. Epub 2015 Apr 23. Toxicol Sci. 2015. PMID: 25911668 Free PMC article.
Cytochrome b 5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b 5 /P450 reductase null (HBRN) mice.
Reed L, Mrizova I, Barta F, Indra R, Moserova M, Kopka K, Schmeiser HH, Wolf CR, Henderson CJ, Stiborova M, Phillips DH, Arlt VM. Reed L, et al. Among authors: mrizova i. Arch Toxicol. 2018 Apr;92(4):1625-1638. doi: 10.1007/s00204-018-2162-7. Epub 2018 Jan 24. Arch Toxicol. 2018. PMID: 29368147 Free PMC article.
Induced expression of microsomal cytochrome b5 determined at mRNA and protein levels in rats exposed to ellipticine, benzo[a]pyrene, and 1-phenylazo-2-naphthol (Sudan I).
Stiborová M, Moserová M, Mrízová I, Dračínská H, Martínek V, Indra R, Frei E, Adam V, Kizek R, Schmeiser HH, Kubáčková K, Arlt VM. Stiborová M, et al. Among authors: mrizova i. Monatsh Chem. 2016;147(5):897-904. doi: 10.1007/s00706-015-1636-z. Epub 2016 Jan 12. Monatsh Chem. 2016. PMID: 27110040 Free PMC article.