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Gene architecture directs splicing outcome in separate nuclear spatial regions.
Mol Cell. 2022 Mar 3;82(5):1021-1034.e8. doi: 10.1016/j.molcel.2022.02.001. Epub 2022 Feb 18.
Mol Cell. 2022.
PMID: 35182478
Free article.
A mixture model for signature discovery from sparse mutation data.
Sason I, Chen Y, Leiserson MDM, Sharan R.
Sason I, et al.
Genome Med. 2021 Nov 1;13(1):173. doi: 10.1186/s13073-021-00988-7.
Genome Med. 2021.
PMID: 34724984
Free PMC article.
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A Biterm Topic Model for Sparse Mutation Data.
Sason I, Chen Y, Leiserson MDM, Sharan R.
Sason I, et al.
Cancers (Basel). 2023 Mar 4;15(5):1601. doi: 10.3390/cancers15051601.
Cancers (Basel). 2023.
PMID: 36900390
Free PMC article.
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A Sticky Multinomial Mixture Model of Strand-Coordinated Mutational Processes in Cancer.
Sason I, Wojtowicz D, Robinson W, Leiserson MDM, Przytycka TM, Sharan R.
Sason I, et al.
iScience. 2020 Mar 27;23(3):100900. doi: 10.1016/j.isci.2020.100900. Epub 2020 Feb 11.
iScience. 2020.
PMID: 32088392
Free PMC article.
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Hidden Markov models lead to higher resolution maps of mutation signature activity in cancer.
Wojtowicz D, Sason I, Huang X, Kim YA, Leiserson MDM, Przytycka TM, Sharan R.
Wojtowicz D, et al. Among authors: sason i.
Genome Med. 2019 Jul 26;11(1):49. doi: 10.1186/s13073-019-0659-1.
Genome Med. 2019.
PMID: 31349863
Free PMC article.
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Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer.
Kim YA, Wojtowicz D, Sarto Basso R, Sason I, Robinson W, Hochbaum DS, Leiserson MDM, Sharan R, Vadin F, Przytycka TM.
Kim YA, et al. Among authors: sason i.
Genome Med. 2020 May 29;12(1):52. doi: 10.1186/s13073-020-00745-2.
Genome Med. 2020.
PMID: 32471470
Free PMC article.
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