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Integrated Protein Solubility Shift Assays for Comprehensive Drug Target Identification on a Proteome-Wide Scale.
Anal Chem. 2023 Sep 19;95(37):13779-13787. doi: 10.1021/acs.analchem.3c00072. Epub 2023 Sep 7.
Anal Chem. 2023.
PMID: 37676971
Here, we develop an iso-pH shift assay (ipHSA) method, a proteome-wide target identification method that detects ligand-induced protein solubility shifts by precipitating proteins with a single concentration of acidic agent followed by protein quantification via data-independent …
Here, we develop an iso-pH shift assay (ipHSA) method, a proteome-wide target identification method that detects ligand-induced protein solu …
Clinical features and outcomes of diabetic foot in Argentina: a longitudinal multicenter study.
Carro GV, Saurral RN, Witman EL, Alterini P, Braver JD, Carrió LM, Issa C, David R.
Carro GV, et al.
Medicina (B Aires). 2023;83(3):428-441.
Medicina (B Aires). 2023.
PMID: 37379540
Free article.
English.
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