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2020 2
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Page 1
Dissecting the role of the NADPH oxidase NOX4 in TGF-beta signaling in hepatocellular carcinoma.
Espinosa-Sotelo R, Fusté NP, Peñuelas-Haro I, Alay A, Pons G, Almodóvar X, Albaladejo J, Sánchez-Vera I, Bonilla-Amadeo R, Dituri F, Serino G, Ramos E, Serrano T, Calvo M, Martínez-Chantar ML, Giannelli G, Bertran E, Fabregat I. Espinosa-Sotelo R, et al. Among authors: sanchez vera i. Redox Biol. 2023 Sep;65:102818. doi: 10.1016/j.redox.2023.102818. Epub 2023 Jul 13. Redox Biol. 2023. PMID: 37463530 Free PMC article.
Fluorizoline-induced apoptosis requires prohibitins in nematodes and human cells.
Saura-Esteller J, Sánchez-Vera I, Núñez-Vázquez S, Jabalquinto-Carrasco J, Cosialls AM, Mendive-Tapia L, Kukhtar D, Martínez-Bueno MD, Lavilla R, Cerón J, Artal-Sanz M, Pons G, Iglesias-Serret D, Gil J. Saura-Esteller J, et al. Among authors: sanchez vera i. Apoptosis. 2021 Feb;26(1-2):83-95. doi: 10.1007/s10495-020-01651-z. Epub 2021 Jan 2. Apoptosis. 2021. PMID: 33387147
The prohibitin-binding compound fluorizoline inhibits mitophagy in cancer cells.
Núñez-Vázquez S, Saura-Esteller J, Sánchez-Vera I, Guilbaud E, Cosialls AM, Pons G, Ricci JE, Iglesias-Serret D, Marchetti S, Gil J. Núñez-Vázquez S, et al. Among authors: sanchez vera i. Oncogenesis. 2021 Sep 27;10(9):64. doi: 10.1038/s41389-021-00352-9. Oncogenesis. 2021. PMID: 34580273 Free PMC article.
The BCL-2 family members NOXA and BIM mediate fluorizoline-induced apoptosis in multiple myeloma cells.
Cosialls AM, Sánchez-Vera I, Pomares H, Perramon-Andújar J, Sanchez-Esteban S, Palmeri CM, Iglesias-Serret D, Saura-Esteller J, Núñez-Vázquez S, Lavilla R, González-Barca EM, Pons G, Gil J. Cosialls AM, et al. Among authors: sanchez vera i. Biochem Pharmacol. 2020 Oct;180:114198. doi: 10.1016/j.bcp.2020.114198. Epub 2020 Aug 13. Biochem Pharmacol. 2020. PMID: 32798467
The prohibitin-binding compound fluorizoline induces the pro-inflammatory cytokines interleukin-8 and interleukin-6 through the activation of JNK and p38 MAP kinases.
Sánchez-Vera I, Saura-Esteller J, Núñez-Vázquez S, Cosialls AM, Ghashghaei O, Lavilla R, Pons G, Gil J, Iglesias-Serret D. Sánchez-Vera I, et al. Biochem Pharmacol. 2023 Dec;218:115860. doi: 10.1016/j.bcp.2023.115860. Epub 2023 Oct 24. Biochem Pharmacol. 2023. PMID: 37884196 Free article.
NOXA upregulation by the prohibitin-binding compound fluorizoline is transcriptionally regulated by integrated stress response-induced ATF3 and ATF4.
Núñez-Vázquez S, Sánchez-Vera I, Saura-Esteller J, Cosialls AM, Noisier AFM, Albericio F, Lavilla R, Pons G, Iglesias-Serret D, Gil J. Núñez-Vázquez S, et al. Among authors: sanchez vera i. FEBS J. 2021 Feb;288(4):1271-1285. doi: 10.1111/febs.15480. Epub 2020 Jul 26. FEBS J. 2021. PMID: 32648994 Free article.
Activation of the Integrated Stress Response and ER Stress Protect from Fluorizoline-Induced Apoptosis in HEK293T and U2OS Cell Lines.
Saura-Esteller J, Sánchez-Vera I, Núñez-Vázquez S, Cosialls AM, Gama-Pérez P, Bhosale G, Mendive-Tapia L, Lavilla R, Pons G, Garcia-Roves PM, Duchen MR, Iglesias-Serret D, Gil J. Saura-Esteller J, et al. Among authors: sanchez vera i. Int J Mol Sci. 2021 Jun 6;22(11):6117. doi: 10.3390/ijms22116117. Int J Mol Sci. 2021. PMID: 34204139 Free PMC article.