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A randomized, double-blind, prospective, placebo-controlled study of the efficacy of a diet supplemented with curcuminoids extract, hydrolyzed collagen and green tea extract in owner's dogs with osteoarthritis.
Comblain F, Barthélémy N, Lefèbvre M, Schwartz C, Lesponne I, Serisier S, Feugier A, Balligand M, Henrotin Y. Comblain F, et al. Among authors: lesponne i. BMC Vet Res. 2017 Dec 20;13(1):395. doi: 10.1186/s12917-017-1317-8. BMC Vet Res. 2017. PMID: 29262825 Free PMC article. Clinical Trial.
Curcuminoids extract, hydrolyzed collagen and green tea extract synergically inhibit inflammatory and catabolic mediator's synthesis by normal bovine and osteoarthritic human chondrocytes in monolayer.
Comblain F, Sanchez C, Lesponne I, Balligand M, Serisier S, Henrotin Y. Comblain F, et al. Among authors: lesponne i. PLoS One. 2015 Mar 23;10(3):e0121654. doi: 10.1371/journal.pone.0121654. eCollection 2015. PLoS One. 2015. PMID: 25799427 Free PMC article.