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Starting at the beginning: endoplasmic reticulum proteostasis and systemic amyloid disease.
Biochem J. 2020 May 15;477(9):1721-1732. doi: 10.1042/BCJ20190312.
Biochem J. 2020.
PMID: 32412081
Review.
ATF6 Activation Reduces Amyloidogenic Transthyretin Secretion through Increased Interactions with Endoplasmic Reticulum Proteostasis Factors.
Mesgarzadeh JS, Romine IC, Smith-Cohen EM, Grandjean JMD, Kelly JW, Genereux JC, Wiseman RL.
Mesgarzadeh JS, et al. Among authors: romine ic.
Cells. 2022 May 17;11(10):1661. doi: 10.3390/cells11101661.
Cells. 2022.
PMID: 35626697
Free PMC article.
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Pharmacologic targeting of plasma cell endoplasmic reticulum proteostasis to reduce amyloidogenic light chain secretion.
Rius B, Mesgarzadeh JS, Romine IC, Paxman RJ, Kelly JW, Wiseman RL.
Rius B, et al. Among authors: romine ic.
Blood Adv. 2021 Feb 23;5(4):1037-1049. doi: 10.1182/bloodadvances.2020002813.
Blood Adv. 2021.
PMID: 33599742
Free PMC article.
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PERK Signaling Regulates Extracellular Proteostasis of an Amyloidogenic Protein During Endoplasmic Reticulum Stress.
Romine IC, Wiseman RL.
Romine IC, et al.
Sci Rep. 2019 Jan 23;9(1):410. doi: 10.1038/s41598-018-37207-0.
Sci Rep. 2019.
PMID: 30675021
Free PMC article.
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