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Mechanical thrombectomy failure in anterior circulation strokes: Outcomes and predictors of favorable outcome.
Marnat G, Gory B, Sibon I, Kyheng M, Labreuche J, Boulouis G, Liegey JS, Caroff J, Eugène F, Naggara O, Consoli A, Mazighi M, Maier B, Richard S, Denier C, Turc G, Lapergue B, Bourcier R; Endovascular Treatment in Ischemic Stroke (ETIS) Investigators. Marnat G, et al. Eur J Neurol. 2022 Sep;29(9):2701-2707. doi: 10.1111/ene.15429. Epub 2022 Jun 18. Eur J Neurol. 2022. PMID: 35648445 Free PMC article.
In multivariable analysis, younger age (odds ratio [OR] 0.96, 95% CI 0.94-0.98, p < 0.001), a lower admission NIHSS (OR 0.87, 95% CI 0.83-0.91, p < 0.001), a lower number of MT passes (OR 0.77, 95% CI 0.77-0.87, p < 0.001), a lower delta …
In multivariable analysis, younger age (odds ratio [OR] 0.96, 95% CI 0.94-0.98, p < 0.001), a lower admission NIHSS (OR 0.87, …
Influence of prior intravenous thrombolysis on outcome after failed mechanical thrombectomy: ETIS registry analysis.
Rozes C, Maier B, Gory B, Bourcier R, Kyheng M, Labreuche J, Consoli A, Mazighi M, Blanc R, Caroff J, Eugene F, Naggara O, Gariel F, Sibon I, Lapergue B, Marnat G; ETIS Registry Investigators. Rozes C, et al. J Neurointerv Surg. 2022 Jul;14(7):688-692. doi: 10.1136/neurintsurg-2021-017867. Epub 2021 Aug 19. J Neurointerv Surg. 2022. PMID: 34413246
Functional outcome was improved in the MT+IVT group compared with the MT alone group, although the difference did not reach statistical significance (23.0% vs 12.9%; adjusted OR=1.82; 95% CI 0.98 to 3.38; p=0.058). However, 3 month mRS shift analysis showed a significant b …
Functional outcome was improved in the MT+IVT group compared with the MT alone group, although the difference did not reach statistical sign …
Thrombectomy in basilar artery occlusions: impact of number of passes and futile reperfusion.
de Havenon A, Elhorany M, Boulouis G, Naggara O, Darcourt J, Clarençon F, Richard S, Marnat G, Bourcier R, Sibon I, Arquizan C, Dargazanli C, Maïer B, Seners P, Lapergue B, Consoli A, Eugene F, Vannier S, Caroff J, Denier C, Boulanger M, Gauberti M, Rouchaud A, Macian F, Rosso C, Turc G, Ozkul-Wermester O, Papagiannaki C, Albucher JF, Le Bras A, Evain S, Wolff V, Pop R, Timsit S, Gentric JC, Bourdain F, Veunac L, Fahed R, Finitsis SN, Gory B; ETIS Registry Investigators. de Havenon A, et al. J Neurointerv Surg. 2023 May;15(5):422-427. doi: 10.1136/neurintsurg-2022-018715. Epub 2022 Apr 21. J Neurointerv Surg. 2023. PMID: 35450929
In patients with 3 passes, the rate of favorable outcome in recanalized versus non-recanalized patients was 50.5% versus 10.0% (p=0.001), while in those with >3 passes it was 16.7% versus 15.2% (p=0.901). ...
In patients with 3 passes, the rate of favorable outcome in recanalized versus non-recanalized patients was 50.5% versus 10.0% (p=0.0 …
Successful thrombectomy is beneficial in patients with pre-stroke disability: Results from an international multicenter cohort study.
Ducroux C, Derex L, Nourredine M, Haesebaert J, Buisson M, Alesefir W, Boisseau W, Daneault N, Deschaintre Y, Diestro JDB, Eker O, Eneling J, Gioia LC, Iancu D, Jacquin G, Odier C, Stapf C, Raymond J, Roy D, Weill A, Lapergue B, Poppe AY; ETIS (Endovascular Treatment in Ischemic Stroke) Investigators. Ducroux C, et al. J Neuroradiol. 2023 Feb;50(1):59-64. doi: 10.1016/j.neurad.2022.03.006. Epub 2022 Mar 25. J Neuroradiol. 2023. PMID: 35341899
Patients with successful reperfusion had a higher proportion of favorable 90-day mRS (27.6% versus 19.6%, p = 0.025) and a lower mortality (48.3% versus 69.6%, p = 0.008) than patients without successful reperfusion. After adjusting for baseline prognostic factors, …
Patients with successful reperfusion had a higher proportion of favorable 90-day mRS (27.6% versus 19.6%, p = 0.025) and a lower mort …
Endovascular reperfusion of M2 occlusions in acute ischemic stroke reduced disability and mortality: ETIS Registry results.
Muszynski P, Anadani M, Richard S, Marnat G, Bourcier R, Sibon I, Dargazanli C, Arquizan C, Maïer B, Blanc R, Lapergue B, Consoli A, Eugene F, Vannier S, Spelle L, Denier C, Boulanger M, Gauberti M, Saleme S, Macian F, Clarençon F, Rosso C, Naggara O, Turc G, Ozkul-Wermester O, Papagiannaki C, Viguier A, Cognard C, Le Bras A, Evain S, Wolff V, Pop R, Timsit S, Gentric JC, Bourdain F, Veunac L, Gory B, Finitsis SN; ETIS Registry Investigators. Muszynski P, et al. J Neurointerv Surg. 2022 May;14(5):neurintsurg-2021-017380. doi: 10.1136/neurintsurg-2021-017380. Epub 2021 May 27. J Neurointerv Surg. 2022. PMID: 34045317
Compared with the non-reperfused patients, reperfused patients had an increased rate of excellent outcome (OR 2.3, 95% CI 0.98 to 5.36; p=0.053), favorable outcome (OR 2.79, 95% CI 1.31 to 5.93; p=0.007), and reduced 90-day mortality (OR 0.39, 95% CI 0.19 to 0.79; …
Compared with the non-reperfused patients, reperfused patients had an increased rate of excellent outcome (OR 2.3, 95% CI 0.98 to 5.36; p
Thrombectomy Complications in Large Vessel Occlusions: Incidence, Predictors, and Clinical Impact in the ETIS Registry.
Happi Ngankou E, Gory B, Marnat G, Richard S, Bourcier R, Sibon I, Dargazanli C, Arquizan C, Maïer B, Blanc R, Lapergue B, Consoli A, Vannier S, Spelle L, Denier C, Boulanger M, Gauberti M, Saleme S, Macian F, Clarençon F, Rosso C, Naggara O, Turc G, Ozkul-Wermester O, Papagiannaki C, Viguier A, Cognard C, Lebras A, Evain S, Wolff V, Pop R, Timsit S, Gentric JC, Bourdain F, Veunac L, Eugène F, Finitsis S; ETIS Registry Investigators†. Happi Ngankou E, et al. Stroke. 2021 Dec;52(12):e764-e768. doi: 10.1161/STROKEAHA.121.034865. Epub 2021 Oct 28. Stroke. 2021. PMID: 34706564
Predictors of ENTs were terminal carotid/tandem occlusion (odds ratio [OR], 5 [95% CI, 2.03-12.31]; P<0.001) and an increased total number of passes (OR, 1.22 [95% CI, 1.05-1.41]; P=0.006). ENTs were associated to worse clinical outcomes (90-day modified Rankin S …
Predictors of ENTs were terminal carotid/tandem occlusion (odds ratio [OR], 5 [95% CI, 2.03-12.31]; P<0.001) and an increased tota …
Clinical Impact and Predictors of Diffusion Weighted Imaging (DWI) Reversal in Stroke Patients with Diffusion Weighted Imaging Alberta Stroke Program Early CT Score 0-5 Treated by Thrombectomy : Diffusion Weighted Imaging Reversal in Large Volume Stroke.
Panni P, Lapergue B, Maïer B, Finitsis S, Clarençon F, Richard S, Marnat G, Bourcier R, Sibon I, Dargazanli C, Blanc R, Consoli A, Eugène F, Vannier S, Spelle L, Denier C, Boulanger M, Gauberti M, Saleme S, Macian F, Rosso C, Naggara O, Turc G, Ozkul-Wermester O, Papagiannaki C, Albucher JF, Darcourt J, Le Bras A, Evain S, Wolff V, Pop R, Timsit S, Gentric JC, Bourdain F, Veunac L, Arquizan C, Gory B; ETIS (Endovascular Treatment in Ischemic Stroke) investigators. Panni P, et al. Clin Neuroradiol. 2022 Dec;32(4):939-950. doi: 10.1007/s00062-022-01156-z. Epub 2022 Apr 12. Clin Neuroradiol. 2022. PMID: 35412044
The DWI reversal (39/211, 18.9%) resulted an independent predictor of both ENI (aOR 3.6, 95% CI 1.2-7.7; p 0.018) and 3-month clinical outcome (aOR for mRS shift: 2.2, 95% CI 1-4.6; p 0.030). Only successful recanalization (mTICI 2c-3) independently predicted DWIr i …
The DWI reversal (39/211, 18.9%) resulted an independent predictor of both ENI (aOR 3.6, 95% CI 1.2-7.7; p 0.018) and 3-month clinica …
Endovascular therapy of acute vertebrobasilar occlusions: influence of first-line strategy in the Endovascular Treatment in Ischemic Stroke (ETIS) Registry.
Bekri I, Finitsis S, Pizzuto S, Maier B, Piotin M, Eker OF, Marnat G, Sibon I, Dargazanli C, Bourcier R, Lapergue B, Pop R, Caroff J, Gory B, Pico F, Consoli A; ETIS Registry investigators. Bekri I, et al. J Neurointerv Surg. 2024 Feb 1:jnis-2023-021325. doi: 10.1136/jnis-2023-021325. Online ahead of print. J Neurointerv Surg. 2024. PMID: 38302421
Procedures performed with CA were shorter compared with CoT (28 vs 47 min, P<0.0001); however, no differences were observed in terms of FPE (CA 43.3% vs CoT 38.4%, P=0.99), and successful final recanalization (mTICI 2b-3, CA 92.4% vs CoT 91.8%, P=0.74) did …
Procedures performed with CA were shorter compared with CoT (28 vs 47 min, P<0.0001); however, no differences were observed in ter …
Impact of Prior Antiplatelet Therapy on Outcomes After Endovascular Therapy for Acute Stroke: Endovascular Treatment in Ischemic Stroke Registry Results.
Couture M, Finitsis S, Marnat G, Richard S, Bourcier R, Constant-Dits-Beaufils P, Dargazanli C, Arquizan C, Mazighi M, Blanc R, Eugène F, Vannier S, Spelle L, Denier C, Touzé E, Barbier C, Saleme S, Macian F, Rosso C, Clarençon F, Naggara O, Turc G, Ozkul-Wermester O, Papagiannaki C, Viguier A, Cognard C, Lebras A, Evain S, Wolff V, Pop R, Timsit S, Gentric JC, Bourdain F, Veunac L, Lapergue B, Consoli A, Gory B, Sibon I; ETIS Registry Investigators*. Couture M, et al. Stroke. 2021 Dec;52(12):3864-3872. doi: 10.1161/STROKEAHA.121.034670. Epub 2021 Sep 20. Stroke. 2021. PMID: 34538083
Rates of complete reperfusion (37.9% in the APT- group versus 42.7 % in the APT+ group; aOR, 1.09 [95% CI, 0.88-1.34]; P=0.41) and periprocedural complication (16.9% versus 13.3%; aOR, 0.90 [95% CI, 0.7-1.2]; P=0.66) did not differ between the two groups. Symptomati …
Rates of complete reperfusion (37.9% in the APT- group versus 42.7 % in the APT+ group; aOR, 1.09 [95% CI, 0.88-1.34]; P=0.41) and pe …