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Proceedings of the 3rd IPLeiria's International Health Congress : Leiria, Portugal. 6-7 May 2016.
Tomás CC, Oliveira E, Sousa D, Uba-Chupel M, Furtado G, Rocha C, Teixeira A, Ferreira P, Alves C, Gisin S, Catarino E, Carvalho N, Coucelo T, Bonfim L, Silva C, Franco D, González JA, Jardim HG, Silva R, Baixinho CL, Presado MªH, Marques MªF, Cardoso ME, Cunha M, Mendes J, Xavier A, Galhardo A, Couto M, Frade JG, Nunes C, Mesquita JR, Nascimento MS, Gonçalves G, Castro C, Mártires A, Monteiro MªJ, Rainho C, Caballero FP, Monago FM, Guerrero JT, Monago RM, Trigo AP, Gutierrez ML, Milanés GM, Reina MG, Villanueva AG, Piñero AS, Aliseda IR, Ramirez FB, Ribeiro A, Quelhas A, Manso C, Caballero FP, Guerrero JT, Monago FM, Santos RB, Jimenez NR, Nuñez CG, Gomez IR, Fernandez MªJL, Marquez LA, Moreno AL, Huertas MªJT, Ramirez FB, Seabra D, Salvador MªC, Braga L, Parreira P, Salgueiro-Oliveira A, Arreguy-Sena C, Oliveira BF, Henriques MªA, Santos J, Lebre S, Marques A, Festas C, Rodrigues S, Ribeiro A, Lumini J, Figueiredo AG, Hernandez-Martinez FJ, Campi L, Quintana-Montesdeoca MªP, Jimenez-Diaz JF, Rodriguez-De-Vera BC, Parente A, Mata MªA, Pereira AMª, Fernandes A, Brás M, Pinto MªR, Parreira P, Basto ML, Rei AC, Mónico LM, Sousa G, Morna C, Freitas O, Freitas G, Jardim A, Vasconcelos … See abstract for full author list ➔ Tomás CC, et al. BMC Health Serv Res. 2016 Jul 6;16 Suppl 3(Suppl 3):200. doi: 10.1186/s12913-016-1423-5. BMC Health Serv Res. 2016. PMID: 27409075 Free PMC article.
Raposo O64 Time management in health professionals Conceicao Rainho, Jose C. Ribeiro, Isabel Barroso, Vitor Rodrigues O65 Financial rewards and wellbeing in primary health care Carmo Neves, Teresa C. ...Marques, Aderito Seixas, Rui Carvalho, Joaquim Ga …
Raposo O64 Time management in health professionals Conceicao Rainho, Jose C. Ribeiro, Isabel Barroso, Vitor Rodrigues O65 Fina …
Staging Parkinson's disease according to the MNCD classification correlates with caregiver burden.
Santos-García D, de Deus Fonticoba T, Cores Bartolomé C, Feal Painceiras MJ, García Díaz I, Alvarado MCÍ, Paz JM, Jesús S, Cosgaya M, Caldentey JG, Caballol N, Legarda I, Hernández Vara J, Cabo I, López Manzanares L, González Aramburu I, Ávila Rivera MA, Gómez Mayordomo V, Nogueira V, Dotor García-Soto J, Borrué C, Solano Vila B, Álvarez Sauco M, Vela L, Escalante S, Cubo E, Mendoza Z, Martínez Castrillo JC, Sánchez Alonso P, Alonso Losada MG, López Ariztegui N, Gastón I, Kulisevsky J, Seijo M, Valero C, Alonso Redondo R, Buongiorno MT, Ordás C, Menéndez-González M, McAfee D, Martinez-Martin P, Mir P; COPPADIS Study Group. Santos-García D, et al. Brain Behav. 2023 Dec;13(12):e3295. doi: 10.1002/brb3.3295. Epub 2023 Nov 8. Brain Behav. 2023. PMID: 37939322 Free PMC article.

A more advanced MNCD stage was associated with a higher score on the ZCBI (p < .0001) and CSI (p < .0001), and a lower score on the PQ-10 (p = .001), but no significant differences were observed in the BDI-II (p = .310) and EUROHIS-QOL8 (p

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A more advanced MNCD stage was associated with a higher score on the ZCBI (p < .0001) and CSI (p < .0001), and a lower s

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Staging Parkinson's Disease According to the MNCD (Motor/Non-motor/Cognition/Dependency) Classification Correlates with Disease Severity and Quality of Life.
Santos-García D, de Deus Fonticoba T, Cores Bartolomé C, Feal Painceiras MJ, Íñiguez-Alvarado MC, García Díaz I, Jesús S, Buongiorno MT, Planellas L, Cosgaya M, García Caldentey J, Caballol N, Legarda I, Hernández Vara J, Cabo I, López Manzanares L, González Aramburu I, Ávila Rivera MA, Gómez Mayordomo V, Nogueira V, Puente V, Dotor García-Soto J, Borrué C, Solano Vila B, Álvarez Sauco M, Vela L, Escalante S, Cubo E, Carrillo Padilla F, Martínez Castrillo JC, Sánchez Alonso P, Alonso Losada MG, López Ariztegui N, Gastón I, Kulisevsky J, Menéndez González M, Seijo M, Ruiz Martínez J, Valero C, Kurtis M, González Ardura J, Alonso Redondo R, Ordás C, López Díaz LM, McAfee D, Calopa M, Carrillo F, Escamilla Sevilla F, Freire-Alvarez E, Gómez Esteban JC, García Ramos R, Luquín MRI, Martínez-Torres I, Sesar Ignacio Á, Martinez-Martin P, Mir P; COPPADIS Study Group. Santos-García D, et al. J Parkinsons Dis. 2023;13(3):379-402. doi: 10.3233/JPD-225073. J Parkinsons Dis. 2023. PMID: 36911948 Free PMC article.
A more advancedMNCD stage was associated with a higher score on the PDQ39SI (p < 0.0001) and a lower score on the PQ-10 (p< 0.0001) and EUROHIS-QOL8 (p< 0.0001). ...

A more advancedMNCD stage was associated with a higher score on the PDQ39SI (p < 0.0001) and a lower score on the PQ-10 (p&

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Contributions to the study of spinocerebellar ataxia type 38 (SCA38).
Gazulla J, Orduna-Hospital E, Benavente I, Rodríguez-Valle A, Osorio-Caicedo P, Alvarez-de Andrés S, García-González E, Fraile-Rodrigo J, Fernández-Tirado FJ, Berciano J. Gazulla J, et al. J Neurol. 2020 Aug;267(8):2288-2295. doi: 10.1007/s00415-020-09840-1. Epub 2020 Apr 20. J Neurol. 2020. PMID: 32314013
RESULTS: Whole-exome sequencing demonstrated a heterozygous variant in ELOVL5, c.779A > G (p.Tyr260Cys), in four tested patients. Intermittent concomitant esotropia and hypertropia caused transient diplopia in one individual each. ...
RESULTS: Whole-exome sequencing demonstrated a heterozygous variant in ELOVL5, c.779A > G (p.Tyr260Cys), in four tested pat …
Real-World Outcomes in Patients with Metastatic Colorectal Cancer in Spain: The RWD-ACROSS Study.
Pericay C, Fernández Montes A, Alonso Orduña V, Macias Declara I, Asensio Martínez E, Rodríguez Salas N, Torres E, Cacho Lavín D, Rodríguez Alonso RM, Falcó E, Oliva JC, Cirera L. Pericay C, et al. Cancers (Basel). 2023 Sep 17;15(18):4603. doi: 10.3390/cancers15184603. Cancers (Basel). 2023. PMID: 37760572 Free PMC article.

Overall median progression-free survival (PFS) was 10.72 months and was longer in patients with left-sided tumors (11.24 vs. 9.31 months (right-sided tumors); p < 0.0001), and in patients receiving either first-line anti-EGFR or anti-VEGF (12.13 and 12.00 vs. 8.98 month

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Overall median progression-free survival (PFS) was 10.72 months and was longer in patients with left-sided tumors (11.24 vs. 9.31 months (ri …
Temporal trends in intraventricular hemorrhage in preterm infants: A Brazilian multicenter cohort.
de Figueiredo Vinagre LE, de Siqueira Caldas JP, Martins Marba ST, Procianoy RS, de Cássia Silveira R, Santiago Rego MA, de Lima Mota Ferreira DM, Sales Alves Junior JM, Dos Santos JPF, Gimenes CB, de Mello E Silva NM, Conde Gonzalez MR, da Silva RPGVC, do Amaral Gomez DBC, do Vale MS, de Souza Rugolo LMS, Meneguel Ogata JF, de Albuquerque Diniz EM, Luz JH, de Almeida JHCL, de Souza MPA, Goncalves Ferri WA. de Figueiredo Vinagre LE, et al. Eur J Paediatr Neurol. 2022 Jul;39:65-73. doi: 10.1016/j.ejpn.2022.05.003. Epub 2022 May 23. Eur J Paediatr Neurol. 2022. PMID: 35696888
RESULTS: Of 6,420 infants, 1951/30.4% (range 27.1-33.8%) had IVH and the disease showed a significant trend towards an overall increase in incidence over time (p = 0.003), especially in three centers. Severe IVH (grade III or IV) occurred in 32.2% (range 29.2-34.5%) of tho …
RESULTS: Of 6,420 infants, 1951/30.4% (range 27.1-33.8%) had IVH and the disease showed a significant trend towards an overall increase in i …
Response to levodopa in Parkinson's disease over time. A 4-year follow-up study.
Santos-García D, de Deus Fonticoba T, Cores Bartolomé C, Feal Painceiras MJ, García Díaz I, Íñiguez Alvarado MC, Paz JM, Jesús S, Cosgaya M, García Caldentey J, Caballol N, Legarda I, González Aramburu I, Ávila Rivera MA, Gómez Mayordomo V, Vela L, Escalante S, Mendoza Z, Martínez Castrillo JC, Alonso PS, Alonso Losada MG, López Ariztegui N, McAfee D, Martinez-Martin P, Mir P; COPPADIS Study Group. Santos-García D, et al. Parkinsonism Relat Disord. 2023 Nov;116:105852. doi: 10.1016/j.parkreldis.2023.105852. Epub 2023 Oct 3. Parkinsonism Relat Disord. 2023. PMID: 37804623
From baseline to 4-year follow-up visit, a significant increase in both the UPDRS-III-OFF (from 27.98 9.58 to 31.75 12.39; p = 0.003) and the UPDRS-III-ON (from 15.92 7.93 to 18.84 8.17; p = 0.006) was observed despite the significant increase in the LEDD (from 896. …
From baseline to 4-year follow-up visit, a significant increase in both the UPDRS-III-OFF (from 27.98 9.58 to 31.75 12.39; p = 0.003) …
Almost 2% of Spanish breast cancer families are associated to germline pathogenic mutations in the ATM gene.
Tavera-Tapia A, Pérez-Cabornero L, Macías JA, Ceballos MI, Roncador G, de la Hoya M, Barroso A, Felipe-Ponce V, Serrano-Blanch R, Hinojo C, Miramar-Gallart MD, Urioste M, Caldés T, Santillan-Garzón S, Benitez J, Osorio A. Tavera-Tapia A, et al. Breast Cancer Res Treat. 2017 Feb;161(3):597-604. doi: 10.1007/s10549-016-4058-7. Epub 2016 Dec 2. Breast Cancer Res Treat. 2017. PMID: 27913932
METHODS: Using whole exome sequencing, we identified a novel germline mutation in the moderate-risk gene ATM (c.5441delT; p.Leu1814Trpfs*14) in a family negative for mutations in BRCA1/2 (BRCAX). ...
METHODS: Using whole exome sequencing, we identified a novel germline mutation in the moderate-risk gene ATM (c.5441delT; p.Le …
High-resolution shotgun proteomics reveals that increased air [CO2] amplifies the acclimation response of coffea species to drought regarding antioxidative, energy, sugar, and lipid dynamics.
Marques I, Rodrigues AP, Gouveia D, Lidon FC, Martins S, Semedo MC, Gaillard JC, Pais IP, Semedo JN, Scotti-Campos P, Reboredo FH, Partelli FL, DaMatta FM, Armengaud J, Ribeiro-Barros AI, Ramalho JC. Marques I, et al. J Plant Physiol. 2022 Sep;276:153788. doi: 10.1016/j.jplph.2022.153788. Epub 2022 Aug 1. J Plant Physiol. 2022. PMID: 35944291 Free article.
For that, plants of Coffea canephora cv. Conilon Clone 153 (CL153) and C. arabica cv. Icatu grown under 380 (aCO(2)) or 700 muL L(-1) (eCO(2)) were exposed to moderate (MWD) and severe (SWD) water deficits. ...
For that, plants of Coffea canephora cv. Conilon Clone 153 (CL153) and C. arabica cv. Icatu grown under 380 (aCO(2)) or 700 muL L(-1) …
Efficacy, safety and visual outcomes of cataract surgeries performed during blindness prevention programs in different locations in Kenya.
Javaloy J, Moya T, Muñoz G, Albarrán-Diego C, Valls-Martínez J, Montalbán R, Murillo MI, Signes-Soler I. Javaloy J, et al. Graefes Arch Clin Exp Ophthalmol. 2021 May;259(5):1215-1224. doi: 10.1007/s00417-021-05084-5. Epub 2021 Jan 29. Graefes Arch Clin Exp Ophthalmol. 2021. PMID: 33512611

Preoperative UDVAs were significantly different with respect to the different geographical areas (Kruskal-Wallis; p < 0.001). The most common intraoperative complication was posterior capsule rupture (incidence, 4.2%, 37 of 881), and the most serious complication was ex

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Preoperative UDVAs were significantly different with respect to the different geographical areas (Kruskal-Wallis; p < 0.001). The

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