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Page 1
The long history of iron in the Universe and in health and disease.
Sheftel AD, Mason AB, Ponka P. Sheftel AD, et al. Biochim Biophys Acta. 2012 Mar;1820(3):161-87. doi: 10.1016/j.bbagen.2011.08.002. Epub 2011 Aug 9. Biochim Biophys Acta. 2012. PMID: 21856378 Free PMC article. Review.
BACKGROUND: Not long after the Big Bang, iron began to play a central role in the Universe and soon became mired in the tangle of biochemistry that is the prima essentia of life. ...SCOPE OF REVIEW: We describe the current understanding of iron metabolism, highlight the ma …
BACKGROUND: Not long after the Big Bang, iron began to play a central role in the Universe and soon became mired in the tangle of bio …
What Can We Learn about Antibody-Drug Conjugates from the T-DM1 Experience?
Esteva FJ, Miller KD, Teicher BA. Esteva FJ, et al. Am Soc Clin Oncol Educ Book. 2015:e117-25. doi: 10.14694/EdBook_AM.2015.35.e117. Am Soc Clin Oncol Educ Book. 2015. PMID: 25993162 Free article.
Technology is continuing to evolve regarding the protein and small molecule components, and it is likely that single chemical entities soon will be the norm for antibody-drug conjugates. Only antibody-radionuclide conjugates and antibody-drug conjugates have reached the re …
Technology is continuing to evolve regarding the protein and small molecule components, and it is likely that single chemical entities so …
The host-seeking inhibitory peptide, Aea-HP-1, is made in the male accessory gland and transferred to the female during copulation.
Naccarati C, Audsley N, Keen JN, Kim JH, Howell GJ, Kim YJ, Isaac RE. Naccarati C, et al. Peptides. 2012 Mar;34(1):150-7. doi: 10.1016/j.peptides.2011.10.027. Epub 2011 Nov 4. Peptides. 2012. PMID: 22080116 Free PMC article.
A. aegypti often mate close to the host and therefore it is possible that male-derived Aea-HP-1 induces short-term changes to female host-seeking behavior to reduce potentially lethal encounters with hosts soon after insemination....
A. aegypti often mate close to the host and therefore it is possible that male-derived Aea-HP-1 induces short-term changes to female host-se …
Epidemiology of nasopharyngeal colonization by S. pneumoniae in Indian infants in the first 2 years of life.
Rupa V, Isaac R, Jalagandeeswaran R, Manoharan A, Rebekah G. Rupa V, et al. Int J Pediatr Otorhinolaryngol. 2014 Oct;78(10):1701-6. doi: 10.1016/j.ijporl.2014.07.024. Epub 2014 Jul 25. Int J Pediatr Otorhinolaryngol. 2014. PMID: 25112164
METHODS: We studied serogroup/serotype (SGT) distribution and antibiotic susceptibility pattern of S. pneumoniae in unvaccinated Indian infants by performing monthly nasopharyngeal swabbing of a birth cohort for 2 years. RESULTS: Colonization began soon after birth and was …
METHODS: We studied serogroup/serotype (SGT) distribution and antibiotic susceptibility pattern of S. pneumoniae in unvaccinated Indian infa …
Morphed emotional faces: emotion detection and misinterpretation in social anxiety.
Heuer K, Lange WG, Isaac L, Rinck M, Becker ES. Heuer K, et al. J Behav Ther Exp Psychiatry. 2010 Dec;41(4):418-25. doi: 10.1016/j.jbtep.2010.04.005. Epub 2010 May 6. J Behav Ther Exp Psychiatry. 2010. PMID: 20511123
Twenty-seven HSA and 30 NAC viewed sequences of neutral faces slowly changing to full-intensity angry, happy, or disgust expressions. Participants were instructed to assign the expression as soon as possible to one of four given emotion categories (angry, contempt, disgust …
Twenty-seven HSA and 30 NAC viewed sequences of neutral faces slowly changing to full-intensity angry, happy, or disgust expressions. Partic …
Ance, a Drosophila angiotensin-converting enzyme homologue, is expressed in imaginal cells during metamorphosis and is regulated by the steroid, 20-hydroxyecdysone.
Siviter RJ, Taylor CA, Cottam DM, Denton A, Dani MP, Milner MJ, Shirras AD, Isaac RE. Siviter RJ, et al. Biochem J. 2002 Oct 1;367(Pt 1):187-93. doi: 10.1042/BJ20020567. Biochem J. 2002. PMID: 12093364 Free PMC article.
Ance expression was particularly strong in the presumptive adult midgut formed as a result of massive proliferation of the imaginal midgut cells soon after pupariation. No Ance transcripts were detected in the midgut of the fully differentiated adult intestine. ...
Ance expression was particularly strong in the presumptive adult midgut formed as a result of massive proliferation of the imaginal midgut c …
Iopamidol and neural tissue metabolism. A comparative in vitro study.
Ekholm SE, Morris TW, Fonte D, Isaac L. Ekholm SE, et al. Invest Radiol. 1986 Oct;21(10):798-801. doi: 10.1097/00004424-198610000-00006. Invest Radiol. 1986. PMID: 3771151
In addition to iohexol, there is another new, nonionic, monomeric, water-soluble CM, iopamidol, soon to be released for clinical use in the United States. Iopamidol, like iohexol, has shown fewer adverse reactions and seems to be safer for myelography than metrizamide. ...
In addition to iohexol, there is another new, nonionic, monomeric, water-soluble CM, iopamidol, soon to be released for clinical use …