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Modic type 2 changes are fibroinflammatory changes with complement system involvement adjacent to degenerated vertebral endplates.
Heggli I, Laux CJ, Mengis T, Karol A, Cornaz F, Herger N, Aradi-Vegh B, Widmer J, Burkhard MD, Farshad-Amacker NA, Pfammatter S, Wolski WE, Brunner F, Distler O, Farshad M, Dudli S. Heggli I, et al. JOR Spine. 2022 Dec 23;6(1):e1237. doi: 10.1002/jsp2.1237. eCollection 2023 Mar. JOR Spine. 2022. PMID: 36994463 Free PMC article.
Bone marrow stromal cells in Modic type 1 changes promote neurite outgrowth.
Mengis T, Herger N, Heggli I, Devan J, Spirig JM, Laux CJ, Brunner F, Farshad M, Distler O, Dudli S. Mengis T, et al. Among authors: heggli i. Front Cell Dev Biol. 2023 Oct 25;11:1286280. doi: 10.3389/fcell.2023.1286280. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 37965581 Free PMC article.
Role of C-reactive protein in the bone marrow of Modic type 1 changes.
Dudli S, Heggli I, Laux CJ, Spirig JM, Wanivenhaus F, Betz M, Germann C, Farshad-Amacker NA, Herger N, Mengis T, Brunner F, Farshad M, Distler O. Dudli S, et al. Among authors: heggli i. J Orthop Res. 2023 May;41(5):1115-1122. doi: 10.1002/jor.25437. Epub 2022 Sep 14. J Orthop Res. 2023. PMID: 36062874
CD90-positive stromal cells associate with inflammatory and fibrotic changes in modic changes.
Dudli S, Karol A, Giudici L, Heggli I, Laux CJ, Spirig JM, Wanivenhaus F, Betz M, Germann C, Farshad-Amacker N, Brunner F, Distler O, Farshad M. Dudli S, et al. Among authors: heggli i. Osteoarthr Cartil Open. 2022 Jun 22;4(3):100287. doi: 10.1016/j.ocarto.2022.100287. eCollection 2022 Sep. Osteoarthr Cartil Open. 2022. PMID: 36474945 Free PMC article.
11 results