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2020 | 4 |
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Page 1
Application of the relationship between pharmacokinetics and pharmacodynamics in drug development and therapeutic equivalence: a PEARRL review.
J Pharm Pharmacol. 2019 Apr;71(4):699-723. doi: 10.1111/jphp.13070. Epub 2019 Feb 22.
J Pharm Pharmacol. 2019.
PMID: 30793317
Review.
Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling to Support Waivers of In Vivo Clinical Studies: Current Status, Challenges, and Opportunities.
Loisios-Konstantinidis I, Dressman J.
Loisios-Konstantinidis I, et al.
Mol Pharm. 2021 Jan 4;18(1):1-17. doi: 10.1021/acs.molpharmaceut.0c00903. Epub 2020 Dec 15.
Mol Pharm. 2021.
PMID: 33320002
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Using Physiologically Based Pharmacokinetic Modeling to Assess the Risks of Failing Bioequivalence Criteria: a Tale of Two Ibuprofen Products.
Loisios-Konstantinidis I, Hens B, Mitra A, Kim S, Chiann C, Cristofoletti R.
Loisios-Konstantinidis I, et al.
AAPS J. 2020 Aug 23;22(5):113. doi: 10.1208/s12248-020-00495-4.
AAPS J. 2020.
PMID: 32830289
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Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling to Predict the Impact of CYP2C9 Genetic Polymorphisms, Co-Medication and Formulation on the Pharmacokinetics and Pharmacodynamics of Flurbiprofen.
Loisios-Konstantinidis I, Cristofoletti R, Jamei M, Turner D, Dressman J.
Loisios-Konstantinidis I, et al.
Pharmaceutics. 2020 Nov 2;12(11):1049. doi: 10.3390/pharmaceutics12111049.
Pharmaceutics. 2020.
PMID: 33147873
Free PMC article.
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Establishing virtual bioequivalence and clinically relevant specifications using in vitro biorelevant dissolution testing and physiologically-based population pharmacokinetic modeling. case example: Naproxen.
Loisios-Konstantinidis I, Cristofoletti R, Fotaki N, Turner DB, Dressman J.
Loisios-Konstantinidis I, et al.
Eur J Pharm Sci. 2020 Feb 15;143:105170. doi: 10.1016/j.ejps.2019.105170. Epub 2019 Nov 27.
Eur J Pharm Sci. 2020.
PMID: 31783158
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