Self-Regulating Adaptive Controller for Oxygen Support to Severe Respiratory Distress Patients and Human Respiratory System Modeling

Diagnostics (Basel). 2023 Mar 3;13(5):967. doi: 10.3390/diagnostics13050967.

Abstract

Uncontrolled breathing is the most critical and challenging situation for a healthcare person to patients. It may be due to simple cough/cold/critical disease to severe respiratory infection of the patients and resulting directly impacts the lungs and damages the alveoli which leads to shortness of breath and also impairs the oxygen exchange. The prolonged respiratory failure in such patients may cause death. In this condition, supportive care of the patients by medicine and a controlled oxygen supply is only the emergency treatment. In this paper, as a part of emergency support, the intelligent set-point modulated fuzzy PI-based model reference adaptive controller (SFPIMRAC) is delineated to control the oxygen supply to uncomforted breathing or respiratory infected patients. The effectiveness of the model reference adaptive controller (MRAC) is enhanced by assimilating the worthiness of fuzzy-based tuning and set-point modulation strategies. Since then, different conventional and intelligent controllers have attempted to regulate the supply of oxygen to respiratory distress patients. To overcome the limitations of previous techniques, researchers created the set-point modulated fuzzy PI-based model reference adaptive controller, which can react instantly to changes in oxygen demand in patients. Nonlinear mathematical formulations of the respiratory system and the exchange of oxygen with time delay are modeled and simulated for study. The efficacy of the proposed SFPIMRAC is tested, with transport delay and set-point variations in the devised respiratory model.

Keywords: mathematical modeling of the human respiratory system with exchange of oxygen; model reference adaptive control; respiratory distress patient; respiratory failure; set-point modulated fuzzy-based control.

Grants and funding

This research received no external funding.