Thermodynamic Properties of 3- and 4-Ethoxyacetanilides between 80 and 480 K

Andrey A Sokolov; Mikhail I Yagofarov; Ilya S Balakhontsev; Ilyas I Nizamov; Timur A Mukhametzyanov; Boris N Solomonov; Yana N Yurkshtovich; Elena N Stepurko

doi:10.3390/molecules28207027

Thermodynamic Properties of 3- and 4-Ethoxyacetanilides between 80 and 480 K

Molecules. 2023 Oct 11;28(20):7027. doi: 10.3390/molecules28207027.

Authors

Andrey A Sokolov¹, Mikhail I Yagofarov¹, Ilya S Balakhontsev¹, Ilyas I Nizamov¹, Timur A Mukhametzyanov¹, Boris N Solomonov¹, Yana N Yurkshtovich², Elena N Stepurko²

Affiliations

¹ Department of Physical Chemistry, Kazan Federal University, Kremlevskaya Str. 18, 420008 Kazan, Russia.
² Chemistry Department, Belarusian State University, 220030 Minsk, Belarus.

Abstract

In this work, we present a comprehensive study of the thermodynamic properties of 3-and 4-ethoxyacetanilides. The heat capacities in crystalline, liquid, and supercooled liquid states from 80 to 475 K were obtained using adiabatic, differential scanning (DSC), and fast scanning (FSC) calorimetries. The fusion enthalpies at T_m were combined from DSC measurement results and the literature data. The fusion enthalpies at 298.15 K were evaluated in two independent ways: adjusted according to Kirchhoff's law of thermochemistry, and using Hess' law. For the latter approach, the enthalpies of the solution in DMF in crystalline and supercooled liquid states were derived. The values obtained by the two methods are consistent with each other. The standard thermodynamic functions (entropy, enthalpy, and Gibbs energy) between 80 and 470 K were calculated.

Keywords: 3-ethoxyacetanilide; adiabatic calorimetry; amides; differential scanning calorimetry; fast scanning calorimetry; fusion enthalpy; heat capacity; phenacetin; solution calorimetry.

Abstract

Grants and funding