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S-adenosyl methionine (SAMe) for depression in adults.
Galizia I, Oldani L, Macritchie K, Amari E, Dougall D, Jones TN, Lam RW, Massei GJ, Yatham LN, Young AH. Galizia I, et al. Cochrane Database Syst Rev. 2016 Oct 10;10(10):CD011286. doi: 10.1002/14651858.CD011286.pub2. Cochrane Database Syst Rev. 2016. PMID: 27727432 Free PMC article. Review.
The exception was that compared to imipramine, fewer participants experienced troublesome adverse effects when treated with parenteral SAMe.The specific adverse effects were not detailed in most of the included studies. There were two reports of mania/hypomania recorded fo …
The exception was that compared to imipramine, fewer participants experienced troublesome adverse effects when treated with parenteral SAMe. …
Topiramate for acute affective episodes in bipolar disorder in adults.
Pigott K, Galizia I, Vasudev K, Watson S, Geddes J, Young AH. Pigott K, et al. Cochrane Database Syst Rev. 2016 Sep 3;9(9):CD003384. doi: 10.1002/14651858.CD003384.pub3. Cochrane Database Syst Rev. 2016. PMID: 27591453 Free PMC article. Review.
Topiramate was compared with placebo and alternative pharmacological treatment as both monotherapy and as adjunctive treatment.Moderate-quality evidence showed topiramate to be no more or less efficacious than placebo as monotherapy, in terms of mean change on Young Mania …
Topiramate was compared with placebo and alternative pharmacological treatment as both monotherapy and as adjunctive treatment.Moderate-qual …