A Review of Natural Polysaccharides: Sources, Characteristics, Properties, Food, and Pharmaceutical Applications

Int J Mol Sci. 2024 Jan 22;25(2):1322. doi: 10.3390/ijms25021322.

Abstract

Natural polysaccharides, which are described in this study, are some of the most extensively used biopolymers in food, pharmaceutical, and medical applications, because they are renewable and have a high level of biocompatibility and biodegradability. The fundamental understanding required to properly exploit polysaccharides potential in the biocomposite, nanoconjugate, and pharmaceutical industries depends on detailed research of these molecules. Polysaccharides are preferred over other polymers because of their biocompatibility, bioactivity, homogeneity, and bioadhesive properties. Natural polysaccharides have also been discovered to have excellent rheological and biomucoadhesive properties, which may be used to design and create a variety of useful and cost-effective drug delivery systems. Polysaccharide-based composites derived from natural sources have been widely exploited due to their multifunctional properties, particularly in drug delivery systems and biomedical applications. These materials have achieved global attention and are in great demand because to their biochemical properties, which mimic both human and animal cells. Although synthetic polymers account for a substantial amount of organic chemistry, natural polymers play a vital role in a range of industries, including biomedical, pharmaceutical, and construction. As a consequence, the current study will provide information on natural polymers, their biological uses, and food and pharmaceutical applications.

Keywords: excipient; food and pharmaceutical applications; natural source; polymers biopolymers.

Publication types

  • Review

MeSH terms

  • Animals
  • Biopolymers / chemistry
  • Drug Delivery Systems*
  • Humans
  • Pharmaceutical Preparations
  • Polymers / chemistry
  • Polysaccharides* / chemistry

Substances

  • Pharmaceutical Preparations
  • Polysaccharides
  • Biopolymers
  • Polymers

Grants and funding

This work was also funded by the Programa Operacional Regional do Centro (CEN-TRO-04-3559-FSE-000162) within the European Social Fund (ESF), CICS-UBI (UIDP/00709/2020) financed by national funds from Fundação para a Ciência e a Tecnologia (FCT), community funds (UIDB/00709/2020) from Fundação La Caixa and Fundação para a Ciência e Tecnologia (FCT) under the Programa Promove Project PD21-00023, and project PRR-C05-i03-I-000143.