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Page 1
Intravenous ferric derisomaltose in patients with heart failure and iron deficiency in the UK (IRONMAN): an investigator-initiated, prospective, randomised, open-label, blinded-endpoint trial.
Kalra PR, Cleland JGF, Petrie MC, Thomson EA, Kalra PA, Squire IB, Ahmed FZ, Al-Mohammad A, Cowburn PJ, Foley PWX, Graham FJ, Japp AG, Lane RE, Lang NN, Ludman AJ, Macdougall IC, Pellicori P, Ray R, Robertson M, Seed A, Ford I; IRONMAN Study Group. Kalra PR, et al. Lancet. 2022 Dec 17;400(10369):2199-2209. doi: 10.1016/S0140-6736(22)02083-9. Epub 2022 Nov 5. Lancet. 2022. PMID: 36347265 Free article. Clinical Trial.
FINDINGS: Between Aug 25, 2016, and Oct 15, 2021, 1869 patients were screened for eligibility, of whom 1137 were randomly assigned to receive intravenous ferric derisomaltose (n=569) or usual care (n=568). Median follow-up was 2.7 years (IQR 1.8-3.6). 336 primary en …
FINDINGS: Between Aug 25, 2016, and Oct 15, 2021, 1869 patients were screened for eligibility, of whom 1137 were randomly assigned to receiv …
Conflict of Interest Disclosures.
[No authors listed] [No authors listed] Global Spine J. 2023 May;13(2_suppl):568S-591S. doi: 10.1177/21925682231173597. Global Spine J. 2023. PMID: 37222100 Free PMC article. No abstract available.
seco-1-Azacubane-2-carboxylic acid-Amide Bond Comparison to Proline.
Fahrenhorst-Jones T, Kong D, Burns JM, Pierens GK, Bernhardt PV, Savage GP, Williams CM. Fahrenhorst-Jones T, et al. J Org Chem. 2023 Sep 15;88(18):12867-12871. doi: 10.1021/acs.joc.3c01264. Epub 2023 Aug 30. J Org Chem. 2023. PMID: 37647582 Review.
seco-1-Azacubane-2-carboxylic acid, an unusual and sterically constrained amino acid, was found to undergo amide bond formation at both the N- and C-termini using proline based bioactive molecule templates as a concept platform....
seco-1-Azacubane-2-carboxylic acid, an unusual and sterically constrained amino acid, was found to undergo amide bond formation at both the …
Reply to S.A. Upadhyaya.
Reddy AT, Krailo MD, Buxton AB, Strother DR, Huang A, Zhou T, Judkins AR, Burger PC, Pollack IF, Williams-Hughes C, Fouladi M, Ho B, Mazewski CM, Lewis VA, Vezina LG, Booth TN, Mahajan A. Reddy AT, et al. J Clin Oncol. 2020 Oct 1;38(28):3353-3354. doi: 10.1200/JCO.20.01573. Epub 2020 Jul 30. J Clin Oncol. 2020. PMID: 32730180 Free PMC article. No abstract available.
The (±)-5-Aza[1.0]triblattane Skeleton via Azetine Cycloaddition.
Su C, Dallaston MA, Watson RD, Fahrenhorst-Jones T, Cameron JP, Pierens GK, Bernhardt PV, Savage GP, Williams CM. Su C, et al. Org Lett. 2024 Apr 12;26(14):2827-2831. doi: 10.1021/acs.orglett.3c03655. Epub 2024 Jan 22. Org Lett. 2024. PMID: 38253345
A series of azetines were synthesized to explore both stability and suitable N-protection. The key step following cycloaddition utilized a noninitiated protonated aminyl radical cyclization to install the final 5-azatriblattane bond, but it was found to be considerably mor …
A series of azetines were synthesized to explore both stability and suitable N-protection. The key step following cycloaddition utili …
Caring for Critically Ill Children With the ICU Liberation Bundle (ABCDEF): Results of the Pediatric Collaborative.
Lin JC, Srivastava A, Malone S, Jennison S, Simino M, Traube C, LaRose K, Kawai Y, Neu L, Kudchadkar S, Wieczorek B, Hajnik K, Kordik CM, Kumar VK, Aghamohammadi S, Arteaga GM, Smith HAB, Spentzas T, Orman A, Landman BM, Valdivia H, Browne H, Fang T, Zimmerman JJ; Society of Critical Care Medicine’s Pediatric ICU Liberation Campaign Collaborative. Lin JC, et al. Pediatr Crit Care Med. 2023 Aug 1;24(8):636-651. doi: 10.1097/PCC.0000000000003262. Epub 2023 May 1. Pediatr Crit Care Med. 2023. PMID: 37125798
The future of International Classification of Diseases coding in steatotic liver disease: An expert panel Delphi consensus statement.
Hagström H, Adams LA, Allen AM, Byrne CD, Chang Y, Duseja A, Grønbæk H, Ismail MH, Jepsen P, Kanwal F, Kramer J, Loomba R, Mark HE, Newsome PN, Rinella ME, Rowe IA, Ryu S, Sanyal A, Schattenberg JM, Serper M, Sheron N, Simon TG, Spearman CW, Tapper EB, Villota-Rivas M, Wild SH, Wong VW, Yilmaz Y, Zelber-Sagi S, Åberg F, Lazarus JV. Hagström H, et al. Hepatol Commun. 2024 Feb 3;8(2):e0386. doi: 10.1097/HC9.0000000000000386. eCollection 2024 Feb 1. Hepatol Commun. 2024. PMID: 38315102 Free PMC article.
BACKGROUND: Following the adoption of new nomenclature for steatotic liver disease, we aimed to build consensus on the use of International Classification of Diseases codes and recommendations for future research and advocacy. METHODS: Through a two-stage Delphi process, a core g …
BACKGROUND: Following the adoption of new nomenclature for steatotic liver disease, we aimed to build consensus on the use of International …
Determining the necessity of phenyl ring π-character in warfarin.
Xing H, Houston SD, Chen X, Jin DY, Savage GP, Tie JK, Williams CM. Xing H, et al. Bioorg Med Chem Lett. 2019 Aug 1;29(15):1954-1956. doi: 10.1016/j.bmcl.2019.05.039. Epub 2019 May 23. Bioorg Med Chem Lett. 2019. PMID: 31147103 Free PMC article.
Continuity of Genetic Risk for Aggressive Behavior Across the Life-Course.
van der Laan CM, Morosoli-García JJ, van de Weijer SGA, Colodro-Conde L; ACTION Consortium; Lupton MK, Mitchell BL, McAloney K, Parker R, Burns JM, Hickie IB, Pool R, Hottenga JJ, Martin NG, Medland SE, Nivard MG, Boomsma DI. van der Laan CM, et al. Behav Genet. 2021 Sep;51(5):592-606. doi: 10.1007/s10519-021-10076-6. Epub 2021 Aug 14. Behav Genet. 2021. PMID: 34390460 Free PMC article.
We test whether genetic influences that explain individual differences in aggression in early life also explain individual differences across the life-course. In two cohorts from The Netherlands (N = 13,471) and Australia (N = 5628), polygenic scores (PGSs) were com …
We test whether genetic influences that explain individual differences in aggression in early life also explain individual differences acros …
44 results