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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 1
1948 1
1951 1
1952 2
1955 2
1957 1
1958 3
1960 2
1961 1
1962 6
1963 2
1964 4
1965 5
1966 2
1967 7
1968 8
1969 5
1970 1
1971 5
1972 7
1973 7
1974 4
1975 6
1976 5
1977 6
1978 13
1979 7
1980 8
1981 11
1982 8
1983 6
1984 9
1985 11
1986 4
1987 12
1988 12
1989 8
1990 15
1991 21
1992 13
1993 12
1994 22
1995 28
1996 24
1997 32
1998 39
1999 36
2000 35
2001 51
2002 47
2003 50
2004 76
2005 76
2006 76
2007 101
2008 113
2009 140
2010 125
2011 135
2012 155
2013 160
2014 200
2015 228
2016 195
2017 165
2018 205
2019 195
2020 243
2021 292
2022 264
2023 237
2024 91

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3,653 results

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Page 1
An historical overview of drug discovery.
Pina AS, Hussain A, Roque AC. Pina AS, et al. Methods Mol Biol. 2009;572:3-12. doi: 10.1007/978-1-60761-244-5_1. Methods Mol Biol. 2009. PMID: 20694682
Polatuzumab vedotin or pinatuzumab vedotin plus rituximab in patients with relapsed or refractory non-Hodgkin lymphoma: final results from a phase 2 randomised study (ROMULUS).
Morschhauser F, Flinn IW, Advani R, Sehn LH, Diefenbach C, Kolibaba K, Press OW, Salles G, Tilly H, Chen AI, Assouline S, Cheson BD, Dreyling M, Hagenbeek A, Zinzani PL, Jones S, Cheng J, Lu D, Penuel E, Hirata J, Wenger M, Chu YW, Sharman J. Morschhauser F, et al. Lancet Haematol. 2019 May;6(5):e254-e265. doi: 10.1016/S2352-3026(19)30026-2. Epub 2019 Mar 29. Lancet Haematol. 2019. PMID: 30935953 Clinical Trial.
BACKGROUND: Antibody-drug conjugates (ADCs) polatuzumab vedotin (pola) and pinatuzumab vedotin (pina) showed clinical activity and tolerability in phase 1 trials. The aim of this multicentre, open-label, phase 2 study was to compare rituximab plus pola (R-pola) or pina …
BACKGROUND: Antibody-drug conjugates (ADCs) polatuzumab vedotin (pola) and pinatuzumab vedotin (pina) showed clinical activity and to …
Leptomeningeal Disease.
Piña Y, Gramatzki D, Forsyth P, Lee EQ, Le Rhun E. Piña Y, et al. Hematol Oncol Clin North Am. 2022 Feb;36(1):189-215. doi: 10.1016/j.hoc.2021.08.009. Epub 2021 Oct 29. Hematol Oncol Clin North Am. 2022. PMID: 34756800 Review. No abstract available.
PINA 3.0: mining cancer interactome.
Du Y, Cai M, Xing X, Ji J, Yang E, Wu J. Du Y, et al. Nucleic Acids Res. 2021 Jan 8;49(D1):D1351-D1357. doi: 10.1093/nar/gkaa1075. Nucleic Acids Res. 2021. PMID: 33231689 Free PMC article.
Therefore, we update the Protein Interaction Network Analysis (PINA) platform to version 3.0, to integrate the unified human interactome with RNA-seq transcriptomes and mass spectrometry-based proteomes across tens of cancer types. ...Furthermore, a brand-new web interface …
Therefore, we update the Protein Interaction Network Analysis (PINA) platform to version 3.0, to integrate the unified human interact …
Influence of Host-Guest and Host-Host Interactions on the Spin-Crossover 3D Hofmann-type Clathrates {Fe(II)(pina)[M(I)(CN)(2)](2)}.xMeOH (M(I) = Ag, Au).
Valverde-Muñoz FJ, Bartual-Murgui C, Piñeiro-López L, Muñoz MC, Real JA. Valverde-Muñoz FJ, et al. Inorg Chem. 2019 Aug 5;58(15):10038-10046. doi: 10.1021/acs.inorgchem.9b01189. Epub 2019 Jul 16. Inorg Chem. 2019. PMID: 31310514
The synthesis, structural characterization and magnetic properties of two new isostructural porous 3D compounds with the general formula {Fe(II)(pina)[M(I)(CN)(2)](2)}.xMeOH (x = 0-5; pina = N-(pyridin-4-yl)isonicotinamide; M(I) = Ag(I) and x 5 (1.xMeOH); M(I) = Au( …
The synthesis, structural characterization and magnetic properties of two new isostructural porous 3D compounds with the general formula {Fe …
PINA v2.0: mining interactome modules.
Cowley MJ, Pinese M, Kassahn KS, Waddell N, Pearson JV, Grimmond SM, Biankin AV, Hautaniemi S, Wu J. Cowley MJ, et al. Nucleic Acids Res. 2012 Jan;40(Database issue):D862-5. doi: 10.1093/nar/gkr967. Epub 2011 Nov 8. Nucleic Acids Res. 2012. PMID: 22067443 Free PMC article.
The Protein Interaction Network Analysis (PINA) platform is a comprehensive web resource, which includes a database of unified protein-protein interaction data integrated from six manually curated public databases, and a set of built-in tools for network construction, filt …
The Protein Interaction Network Analysis (PINA) platform is a comprehensive web resource, which includes a database of unified protei …
PINA is essential for growth and positively influences NIMA function in Aspergillus nidulans.
Joseph JD, Daigle SN, Means AR. Joseph JD, et al. J Biol Chem. 2004 Jul 30;279(31):32373-84. doi: 10.1074/jbc.M405415200. Epub 2004 Jun 3. J Biol Chem. 2004. PMID: 15178679 Free article.
Here we explore the physiological roles of the Pin1 orthologue, PINA, in A. nidulans and evaluate the relevance of the interaction of PINA with NIMA in this fungus. We find pinA to be an essential gene in A. nidulans. In addition, when PINA levels are …
Here we explore the physiological roles of the Pin1 orthologue, PINA, in A. nidulans and evaluate the relevance of the interaction of …
PinA inhibits ATP hydrolysis and energy-dependent protein degradation by Lon protease.
Hilliard JJ, Simon LD, Van Melderen L, Maurizi MR. Hilliard JJ, et al. J Biol Chem. 1998 Jan 2;273(1):524-7. doi: 10.1074/jbc.273.1.524. J Biol Chem. 1998. PMID: 9417111 Free article.
Thus, PinA does not block the proteolytic active site or the allosteric protein-binding site on Lon. ...These data suggest that PinA does not bind at the ATPase active site of Lon and does not interfere with nucleotide binding to the enzyme. ...
Thus, PinA does not block the proteolytic active site or the allosteric protein-binding site on Lon. ...These data suggest that Pi …
Prevalence and Incidence of Pre-HF Among Hispanics/Latinos.
Pandey A, Keshvani N, Piña IL. Pandey A, et al. JACC Heart Fail. 2023 Aug;11(8 Pt 1):958-960. doi: 10.1016/j.jchf.2023.05.021. Epub 2023 Jul 5. JACC Heart Fail. 2023. PMID: 37410011 No abstract available.
3,653 results