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Showing results for hemin go
Search for Hyemin Go instead (1 results)
Intracellular hemin is a potent inhibitor of the voltage-gated potassium channel Kv10.1.
Sahoo N, Yang K, Coburger I, Bernert A, Swain SM, Gessner G, Kappl R, Kühl T, Imhof D, Hoshi T, Schönherr R, Heinemann SH. Sahoo N, et al. Sci Rep. 2022 Aug 27;12(1):14645. doi: 10.1038/s41598-022-18975-2. Sci Rep. 2022. PMID: 36030326 Free PMC article.
In recent years, there has been a growing recognition of heme as a non-genomic modulator of ion channel functions. Here, we show that intracellular free heme and hemin modulate human ether a go-go (hEAG1, Kv10.1) voltage-gated potassium channels. ...Our resul …
In recent years, there has been a growing recognition of heme as a non-genomic modulator of ion channel functions. Here, we show that intrac …
Ursolic Acid Alleviates Neuroinflammation after Intracerebral Hemorrhage by Mediating Microglial Pyroptosis via the NF-κB/NLRP3/GSDMD Pathway.
Lei P, Li Z, Hua Q, Song P, Gao L, Zhou L, Cai Q. Lei P, et al. Int J Mol Sci. 2023 Sep 30;24(19):14771. doi: 10.3390/ijms241914771. Int J Mol Sci. 2023. PMID: 37834220 Free PMC article.
Online databases were used to obtain potential therapeutic targets of ursolic acid for the treatment of cerebral hemorrhage, and possible mechanisms were analyzed by KEGG, GO, and molecular docking. A rat model of cerebral hemorrhage was established using collagenase, and …
Online databases were used to obtain potential therapeutic targets of ursolic acid for the treatment of cerebral hemorrhage, and possible me …
Magnetic graphene oxide-supported hemin as peroxidase probe for sensitive detection of thiols in extracts of cancer cells.
Bi S, Zhao T, Jia X, He P. Bi S, et al. Biosens Bioelectron. 2014 Jul 15;57:110-6. doi: 10.1016/j.bios.2014.01.025. Epub 2014 Feb 8. Biosens Bioelectron. 2014. PMID: 24561525
Magnetic graphene oxide (GO)-hemin probes containing disulfide bonds are simply and effectively synthesized through amide reaction to covalently link magnetic particles to GO surface and pi-pi stacking interaction between hemin and GO to immobil …
Magnetic graphene oxide (GO)-hemin probes containing disulfide bonds are simply and effectively synthesized through amide reac …
Hemin as a novel candidate for treating COVID-19 via heme oxygenase-1 induction.
Kim DH, Ahn HS, Go HJ, Kim DY, Kim JH, Lee JB, Park SY, Song CS, Lee SW, Ha SD, Choi C, Choi IS. Kim DH, et al. Sci Rep. 2021 Nov 2;11(1):21462. doi: 10.1038/s41598-021-01054-3. Sci Rep. 2021. PMID: 34728736 Free PMC article.
To confirm whether HO-1 suppresses SARS-CoV-2 infection, we assessed the antiviral activity of hemin, an effective and safe HO-1 inducer, in SARS-CoV-2 infection. We found that treatment with hemin efficiently suppressed SARS-CoV-2 replication (selectivity index: 24 …
To confirm whether HO-1 suppresses SARS-CoV-2 infection, we assessed the antiviral activity of hemin, an effective and safe HO-1 indu …
Dual Ni/Co-hemin metal-organic framework-PrGO for high-performance asymmetric hybrid supercapacitor.
Mousaabadi KZ, Ensafi AA, Naghsh E, Hu JS, Rezaei B. Mousaabadi KZ, et al. Sci Rep. 2023 Aug 1;13(1):12422. doi: 10.1038/s41598-023-39553-0. Sci Rep. 2023. PMID: 37528177 Free PMC article.
In this study, we conducted direct synthesis of a dual metal-organic framework (Ni/Co-Hemin MOF) on phosphorous-doped reduced graphene oxide (PrGO) to serve as an active material in high-performance asymmetrical supercapacitors. ...Our comprehensive characterization and co …
In this study, we conducted direct synthesis of a dual metal-organic framework (Ni/Co-Hemin MOF) on phosphorous-doped reduced graphen …
In vitro cytotoxicity evaluation of graphene oxide from the peroxidase-like activity perspective.
Zhang W, Sun Y, Lou Z, Song L, Wu Y, Gu N, Zhang Y. Zhang W, et al. Colloids Surf B Biointerfaces. 2017 Mar 1;151:215-223. doi: 10.1016/j.colsurfb.2016.12.025. Epub 2016 Dec 19. Colloids Surf B Biointerfaces. 2017. PMID: 28013165
In this study, PEGylated graphene oxide (PEG-GO)-hemin composite structure was constructed. Hemin in the form of nanoscaled aggregates were immobilized on PEG-GO sheets by the pi-pi stacking super-molecular interaction. Via catalyzing the oxidation of …
In this study, PEGylated graphene oxide (PEG-GO)-hemin composite structure was constructed. Hemin in the form of nanosc …
Synthesis of a hemin-containing copolymer as a novel immunostimulator that induces IFN-gamma production.
Hoshi K, Yamazaki T, Yoshikawa C, Tsugawa W, Ikebukuro K, Sode K. Hoshi K, et al. Int J Nanomedicine. 2018 Aug 2;13:4461-4472. doi: 10.2147/IJN.S166259. eCollection 2018. Int J Nanomedicine. 2018. PMID: 30122920 Free PMC article.
RESULTS: NIPAM-hemin was soluble and showed no cytotoxicity in vitro. The NIPAM-hemin copolymer induced the production of interferon (IFN)-gamma and interleukin (IL)-6 from peripheral blood mononuclear cells, although hemin and the NIPAM monomer individually …
RESULTS: NIPAM-hemin was soluble and showed no cytotoxicity in vitro. The NIPAM-hemin copolymer induced the production of inte …
Antioxidants protect against gingival overgrowth induced by cyclosporine A.
Chin YT, Tu HP, Lin CY, Kuo PJ, Chiu HC, Liu SH, Lee SY, Fu E. Chin YT, et al. J Periodontal Res. 2021 Apr;56(2):397-407. doi: 10.1111/jre.12832. Epub 2021 Jan 14. J Periodontal Res. 2021. PMID: 33448057
OBJECTIVE: We investigated the importance of reactive oxygen species (ROS) on developing gingival overgrowth (GO) and then introduced the antioxidant strategy to prevent, or even reduce GO. ...Although it has been broadly investigated, the exact pathogenesis of the …
OBJECTIVE: We investigated the importance of reactive oxygen species (ROS) on developing gingival overgrowth (GO) and then introduced …
Enhanced reversible redox activity of hemin on cellulose microfiber integrated reduced graphene oxide for H(2)O(2) biosensor applications.
Palanisamy S, Velusamy V, Chen SW, Yang TCK, Balu S, Banks CE. Palanisamy S, et al. Carbohydr Polym. 2019 Jan 15;204:152-160. doi: 10.1016/j.carbpol.2018.10.001. Epub 2018 Oct 4. Carbohydr Polym. 2019. PMID: 30366526
This paper reports the fabrication of novel H(2)O(2) biosensor using a hemin immobilized reduced graphene oxide-cellulose microfiber composite (hemin/RGO-CMF). ...Cyclic voltammetry results revealed that the hemin/RGO-CMF composite shows a better redox electr …
This paper reports the fabrication of novel H(2)O(2) biosensor using a hemin immobilized reduced graphene oxide-cellulose microfiber …
Pivotal Role of GSTO2 in Ferroptotic Neuronal Injury After Intracerebral Hemorrhage.
Lin L, Li XN, Xie ZY, Hu YZ, Long QS, Wen YQ, Wei XB, Zhang LY, Li XS. Lin L, et al. J Mol Neurosci. 2024 Feb 22;74(1):24. doi: 10.1007/s12031-023-02187-y. J Mol Neurosci. 2024. PMID: 38386166 Free PMC article.
Based on the GO data, we performed GSEA and found that the glutathione metabolic process was significantly enriched in the hemin phenotype. Notably, the expression of glutathione S-transferase omega (GSTO2), which is involved in glutathione metabolism, was decreased …
Based on the GO data, we performed GSEA and found that the glutathione metabolic process was significantly enriched in the hemin …
49 results