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MR spectroscopy in pediatric neuroradiology.
Liserre R, Pinelli L, Gasparotti R. Liserre R, et al. Transl Pediatr. 2021 Apr;10(4):1169-1200. doi: 10.21037/tp-20-445. Transl Pediatr. 2021. PMID: 34012861 Free PMC article. Review.
In this review we will illustrate the basic principles and clinical applications of brain proton (H(1); hydrogen) MRS (H(1)MRS), by now the only MRS method widely available in clinical practice. ...
In this review we will illustrate the basic principles and clinical applications of brain proton (H(1); hydrogen) MRS (H(1)MRS), by n …
Effect of Bleaching Method and Curing Time on the Surface Microhardness of Microhybrid Composite Resin.
Mohammadi N, Alavi FN, Rikhtehgaran S, Chaharom MEE, Salari A, Kimyai S, Bahari M. Mohammadi N, et al. Maedica (Bucur). 2020 Sep;15(3):359-364. doi: 10.26574/maedica.2020.15.3.359. Maedica (Bucur). 2020. PMID: 33312252 Free PMC article.
Then, each group was divided into three subgroups: control (distilled water), home bleaching (15% carbamide peroxide) and office bleaching (40% hydrogen peroxide). Surface microhardness of the samples was determined by using Vickers hardness test both at baseline an …
Then, each group was divided into three subgroups: control (distilled water), home bleaching (15% carbamide peroxide) and office blea …
Predicting the Drug Clearance Pathway with Structural Descriptors.
Kaboudi N, Shayanfar A. Kaboudi N, et al. Eur J Drug Metab Pharmacokinet. 2022 May;47(3):363-369. doi: 10.1007/s13318-021-00748-3. Epub 2022 Feb 11. Eur J Drug Metab Pharmacokinet. 2022. PMID: 35147854

RESULTS: The results of this study indicate that compounds with logD(7.4) > 1 or with zero or one hydrogen-bond donor undergo hepatic metabolism, whereas the clearance pathway for chemicals with logD(7.4) < - 2 is renal elimination. ...The main descriptors that are u

RESULTS: The results of this study indicate that compounds with logD(7.4) > 1 or with zero or one hydrogen-bond donor undergo hepa …
High-molecular-weight polymers from dietary fiber drive aggregation of particulates in the murine small intestine.
Preska Steinberg A, Datta SS, Naragon T, Rolando JC, Bogatyrev SR, Ismagilov RF. Preska Steinberg A, et al. Elife. 2019 Jan 22;8:e40387. doi: 10.7554/eLife.40387. Elife. 2019. PMID: 30666958 Free PMC article.
This work suggests that the molecular weight and concentration of dietary polymers play an underappreciated role in shaping the physicochemical environment of the gut. EDITORIAL NOTE: This article has been through an editorial process in which the authors decide how …
This work suggests that the molecular weight and concentration of dietary polymers play an underappreciated role in shaping the physicochemi …
In silico models to predict tubular secretion or reabsorption clearance pathway using physicochemical properties and structural characteristics.
Kaboudi N, Alizadeh AA, Shayanfar A. Kaboudi N, et al. Xenobiotica. 2022 Apr;52(4):346-352. doi: 10.1080/00498254.2022.2076632. Epub 2022 May 30. Xenobiotica. 2022. PMID: 35543185
Different structural descriptors (VolSurf descriptors, Abraham solvation parameters, data warrior descriptors, logarithm of distribution coefficient at pH = 7.4 (logD(7.4))) were applied to develop a mechanistic model for estimating renal clearance class whether its secretion or …
Different structural descriptors (VolSurf descriptors, Abraham solvation parameters, data warrior descriptors, logarithm of distribution coe …
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