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Induction of Noxa-mediated apoptosis by modified vaccinia virus Ankara depends on viral recognition by cytosolic helicases, leading to IRF-3/IFN-β-dependent induction of pro-apoptotic Noxa.
Eitz Ferrer P, Potthoff S, Kirschnek S, Gasteiger G, Kastenmüller W, Ludwig H, Paschen SA, Villunger A, Sutter G, Drexler I, Häcker G. Eitz Ferrer P, et al. Among authors: ludwig h. PLoS Pathog. 2011 Jun;7(6):e1002083. doi: 10.1371/journal.ppat.1002083. Epub 2011 Jun 16. PLoS Pathog. 2011. PMID: 21698224 Free PMC article.
Viral host-range factor C7 or K1 is essential for modified vaccinia virus Ankara late gene expression in human and murine cells, irrespective of their capacity to inhibit protein kinase R-mediated phosphorylation of eukaryotic translation initiation factor 2alpha.
Backes S, Sperling KM, Zwilling J, Gasteiger G, Ludwig H, Kremmer E, Schwantes A, Staib C, Sutter G. Backes S, et al. Among authors: ludwig h. J Gen Virol. 2010 Feb;91(Pt 2):470-82. doi: 10.1099/vir.0.015347-0. Epub 2009 Oct 21. J Gen Virol. 2010. PMID: 19846675
17 results