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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 2
1978 1
1979 1
1980 1
1981 1
1983 2
1984 2
1985 1
1987 1
1988 3
1989 1
1990 1
1992 1
1993 2
1994 2
1995 1
1996 4
1997 2
1998 2
2000 3
2001 3
2002 2
2003 1
2004 2
2005 5
2006 6
2007 10
2008 5
2009 6
2010 6
2011 6
2012 6
2013 7
2014 6
2015 8
2016 2
2017 2
2018 2
2019 2
2020 1
2021 6
2022 5
2023 3
2024 0

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122 results

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Page 1
HLA and rheumatoid arthritis: how do they connect?
van Heemst J, van der Woude D, Huizinga TW, Toes RE. van Heemst J, et al. Ann Med. 2014 Aug;46(5):304-10. doi: 10.3109/07853890.2014.907097. Epub 2014 May 9. Ann Med. 2014. PMID: 24813459 Review.
These two disease phenotypes are associated with different environmental and genetic risk factors and clinical parameters. The HLA class II locus is the most important risk factor for ACPA-positive RA (ACPA+ RA). ...We present and discuss several models and underlying data …
These two disease phenotypes are associated with different environmental and genetic risk factors and clinical parameters. The HLA cl …
HLA class II and rheumatoid arthritis: the bumpy road of revelation.
Kampstra ASB, Toes REM. Kampstra ASB, et al. Immunogenetics. 2017 Aug;69(8-9):597-603. doi: 10.1007/s00251-017-0987-5. Epub 2017 Jul 11. Immunogenetics. 2017. PMID: 28695293 Free PMC article. Review.
For ACPA(+) RA disease, the genetic factors associating with disease mainly comprised of human leukocyte antigen (HLA) class II molecules. The predisposing HLA-DR alleles have been depicted as the 'HLA Shared Epitope (SE) alleles', as these alleles encode a s …
For ACPA(+) RA disease, the genetic factors associating with disease mainly comprised of human leukocyte antigen (HLA) class II molec …
Determining in which pre-arthritis stage HLA-shared epitope alleles and smoking exert their effect on the development of rheumatoid arthritis.
Wouters F, Maurits MP, van Boheemen L, Verstappen M, Mankia K, Matthijssen XME, Dorjée AL, Emery P, Knevel R, van Schaardenburg D, Toes REM, van der Helm-van Mil AHM. Wouters F, et al. Ann Rheum Dis. 2022 Jan;81(1):48-55. doi: 10.1136/annrheumdis-2021-220546. Epub 2021 Jul 20. Ann Rheum Dis. 2022. PMID: 34285049 Free PMC article. Review.
During follow-up, HLA-SE associated with IA development (HR 1.86 (95% CI: 1.23 to 2.82)), in contrast to smoking. ...Longitudinally, AAPA associated with IA development independent from ACPA and RF (HR 1.79 (95% CI: 1.02 to 3.16)), anti-CarP did not. CONCLUSIONS: HLA …
During follow-up, HLA-SE associated with IA development (HR 1.86 (95% CI: 1.23 to 2.82)), in contrast to smoking. ...Longitudinally, …
Redefining the HLA and RA association: to be or not to be anti-CCP positive.
de Vries RR, Huizinga TW, Toes RE. de Vries RR, et al. J Autoimmun. 2005;25 Suppl:21-5. doi: 10.1016/j.jaut.2005.09.005. Epub 2005 Oct 27. J Autoimmun. 2005. PMID: 16257178 Review.
Based on twin studies the contribution of genetic factors to the pathogenesis has been estimated to be about 60%. The main genetic contribution (about 40%) comes from the HLA complex. An association between HLA-DR4 and RA was already documented almost 30 years ago. …
Based on twin studies the contribution of genetic factors to the pathogenesis has been estimated to be about 60%. The main genetic contribut …
Protection against rheumatoid arthritis by HLA: nature and nurture.
Feitsma AL, van der Helm-van Mil AH, Huizinga TW, de Vries RR, Toes RE. Feitsma AL, et al. Ann Rheum Dis. 2008 Dec;67 Suppl 3:iii61-3. doi: 10.1136/ard.2008.098509. Ann Rheum Dis. 2008. PMID: 19022816 Review.
Rheumatoid arthritis (RA) is a complex genetic disorder in which the HLA region contributes most to the genetic risk. HLA-DRB1 molecules containing the amino acid sequence QKRAA/QRRAA/RRRAA (ie, HLA-DRB1*0101, *0102, *0401, *0404, *0405, *0408, *0410, *1001 a …
Rheumatoid arthritis (RA) is a complex genetic disorder in which the HLA region contributes most to the genetic risk. HLA-DRB1 …
Graves’ Disease: Complications.
Bartalena L. Bartalena L. 2018 Feb 20. In: Feingold KR, Anawalt B, Blackman MR, Boyce A, Chrousos G, Corpas E, de Herder WW, Dhatariya K, Dungan K, Hofland J, Kalra S, Kaltsas G, Kapoor N, Koch C, Kopp P, Korbonits M, Kovacs CS, Kuohung W, Laferrère B, Levy M, McGee EA, McLachlan R, New M, Purnell J, Sahay R, Shah AS, Singer F, Sperling MA, Stratakis CA, Trence DL, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000–. 2018 Feb 20. In: Feingold KR, Anawalt B, Blackman MR, Boyce A, Chrousos G, Corpas E, de Herder WW, Dhatariya K, Dungan K, Hofland J, Kalra S, Kaltsas G, Kapoor N, Koch C, Kopp P, Korbonits M, Kovacs CS, Kuohung W, Laferrère B, Levy M, McGee EA, McLachlan R, New M, Purnell J, Sahay R, Shah AS, Singer F, Sperling MA, Stratakis CA, Trence DL, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000–. PMID: 25905406 Free Books & Documents. Review.
Topical glucocorticoids are usually effective. Thyroid acropachy (clubbing of fingers and toes, with swelling of hands and feet) is an extremely rare conditions, for which no treatment is available. ...
Topical glucocorticoids are usually effective. Thyroid acropachy (clubbing of fingers and toes, with swelling of hands and feet) is a …
[Psoriatic onycho-pachydermo-periostitis].
De Pontville M, Dompmartin A, De Raucourt S, Macro M, Rémond B, Leroy D. De Pontville M, et al. Ann Dermatol Venereol. 1993;120(3):229-32. Ann Dermatol Venereol. 1993. PMID: 8239363 French.
Two cases of onycho-pachydermo-periostitis are described. We report the first one with all the fingers and toes concerned....
Two cases of onycho-pachydermo-periostitis are described. We report the first one with all the fingers and toes concerned....
Genetic predisposition (HLA-SE) is associated with ACPA-IgG variable domain glycosylation in the predisease phase of RA.
Kissel T, van Wesemael TJ, Lundquist A, Kokkonen H, Kawakami A, Tamai M, van Schaardenburg D, Wuhrer M, Huizinga TW, Scherer HU, van der Woude D, Rantapää-Dahlqvist S, Toes REM. Kissel T, et al. Ann Rheum Dis. 2022 Jan;81(1):141-143. doi: 10.1136/annrheumdis-2021-220841. Epub 2021 Aug 12. Ann Rheum Dis. 2022. PMID: 34385139 No abstract available.
Coeliac disease and rheumatoid arthritis: similar mechanisms, different antigens.
Koning F, Thomas R, Rossjohn J, Toes RE. Koning F, et al. Nat Rev Rheumatol. 2015 Aug;11(8):450-61. doi: 10.1038/nrrheum.2015.59. Epub 2015 May 19. Nat Rev Rheumatol. 2015. PMID: 25986717 Review.
Rheumatoid arthritis (RA) and coeliac disease are inflammatory diseases that both have a strong association with class II HLAs: individuals carrying HLA-DQ2.5 and/or HLA-DQ8 alleles have an increased risk of developing coeliac disease, whereas those carrying HLA …
Rheumatoid arthritis (RA) and coeliac disease are inflammatory diseases that both have a strong association with class II HLAs: individuals …
122 results