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Page 1
Antibacterial properties of 3-(phenylsulfonyl)-2-pyrazinecarbonitrile.
Bioorg Med Chem Lett. 2015 Nov 15;25(22):5203-7. doi: 10.1016/j.bmcl.2015.09.066. Epub 2015 Sep 30.
Bioorg Med Chem Lett. 2015.
PMID: 26459212
Free PMC article.
6-Furopyridine Hexamethylene Amiloride Is a Non-Selective P2X7 Receptor Antagonist.
Cuthbertson P, Elhage A, Al-Rifai D, Sophocleous RA, Turner RJ, Aboelela A, Majed H, Bujaroski RS, Jalilian I, Kelso MJ, Watson D, Buckley BJ, Sluyter R.
Cuthbertson P, et al. Among authors: majed h.
Biomolecules. 2022 Sep 16;12(9):1309. doi: 10.3390/biom12091309.
Biomolecules. 2022.
PMID: 36139148
Free PMC article.
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Automated Patch Clamp Screening of Amiloride and 5-N,N-Hexamethyleneamiloride Analogs Identifies 6-Iodoamiloride as a Potent Acid-Sensing Ion Channel Inhibitor.
Finol-Urdaneta RK, McArthur JR, Aboelela A, Bujaroski RS, Majed H, Rangel A, Adams DJ, Ranson M, Kelso MJ, Buckley BJ.
Finol-Urdaneta RK, et al. Among authors: majed h.
Mol Pharm. 2023 Jul 3;20(7):3367-3379. doi: 10.1021/acs.molpharmaceut.2c01083. Epub 2023 Jun 1.
Mol Pharm. 2023.
PMID: 37260417
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Systematic evaluation of structure-property relationships and pharmacokinetics in 6-(hetero)aryl-substituted matched pair analogs of amiloride and 5-(N,N-hexamethylene)amiloride.
Buckley BJ, Aboelela A, Majed H, Bujaroski RS, White KL, Powell AK, Wang W, Katneni K, Saunders J, Shackleford DM, Charman SA, Cook GM, Kelso MJ, Ranson M.
Buckley BJ, et al. Among authors: majed h.
Bioorg Med Chem. 2021 May 1;37:116116. doi: 10.1016/j.bmc.2021.116116. Epub 2021 Mar 23.
Bioorg Med Chem. 2021.
PMID: 33799173
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6-Substituted amiloride derivatives as inhibitors of the urokinase-type plasminogen activator for use in metastatic disease.
Buckley BJ, Majed H, Aboelela A, Minaei E, Jiang L, Fildes K, Cheung CY, Johnson D, Bachovchin D, Cook GM, Huang M, Ranson M, Kelso MJ.
Buckley BJ, et al. Among authors: majed h.
Bioorg Med Chem Lett. 2019 Dec 15;29(24):126753. doi: 10.1016/j.bmcl.2019.126753. Epub 2019 Oct 28.
Bioorg Med Chem Lett. 2019.
PMID: 31679971
Free PMC article.
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Screening of 5- and 6-Substituted Amiloride Libraries Identifies Dual-uPA/NHE1 Active and Single Target-Selective Inhibitors.
Buckley BJ, Kumar A, Aboelela A, Bujaroski RS, Li X, Majed H, Fliegel L, Ranson M, Kelso MJ.
Buckley BJ, et al. Among authors: majed h.
Int J Mol Sci. 2021 Mar 15;22(6):2999. doi: 10.3390/ijms22062999.
Int J Mol Sci. 2021.
PMID: 33804289
Free PMC article.
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Structure-activity relationships of pyrazole-4-carbodithioates as antibacterials against methicillin-resistant Staphylococcus aureus.
Majed H, Johnston T, Kelso C, Monachino E, Jergic S, Dixon NE, Mylonakis E, Kelso MJ.
Majed H, et al.
Bioorg Med Chem Lett. 2018 Dec 1;28(22):3526-3528. doi: 10.1016/j.bmcl.2018.09.038. Epub 2018 Oct 3.
Bioorg Med Chem Lett. 2018.
PMID: 30297281
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