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Macrophage-derived angiopoietin-like protein 2 accelerates development of abdominal aortic aneurysm.
Tazume H, Miyata K, Tian Z, Endo M, Horiguchi H, Takahashi O, Horio E, Tsukano H, Kadomatsu T, Nakashima Y, Kunitomo R, Kaneko Y, Moriyama S, Sakaguchi H, Okamoto K, Hara M, Yoshinaga T, Yoshimura K, Aoki H, Araki K, Hao H, Kawasuji M, Oike Y. Tazume H, et al. Among authors: tsukano h. Arterioscler Thromb Vasc Biol. 2012 Jun;32(6):1400-9. doi: 10.1161/ATVBAHA.112.247866. Epub 2012 May 3. Arterioscler Thromb Vasc Biol. 2012. PMID: 22556334
Mitochondrial dysfunction and increased reactive oxygen species impair insulin secretion in sphingomyelin synthase 1-null mice.
Yano M, Watanabe K, Yamamoto T, Ikeda K, Senokuchi T, Lu M, Kadomatsu T, Tsukano H, Ikawa M, Okabe M, Yamaoka S, Okazaki T, Umehara H, Gotoh T, Song WJ, Node K, Taguchi R, Yamagata K, Oike Y. Yano M, et al. Among authors: tsukano h. J Biol Chem. 2011 Feb 4;286(5):3992-4002. doi: 10.1074/jbc.M110.179176. Epub 2010 Nov 29. J Biol Chem. 2011. PMID: 21115496 Free PMC article.
Angiopoietin-like protein 2 promotes chronic adipose tissue inflammation and obesity-related systemic insulin resistance.
Tabata M, Kadomatsu T, Fukuhara S, Miyata K, Ito Y, Endo M, Urano T, Zhu HJ, Tsukano H, Tazume H, Kaikita K, Miyashita K, Iwawaki T, Shimabukuro M, Sakaguchi K, Ito T, Nakagata N, Yamada T, Katagiri H, Kasuga M, Ando Y, Ogawa H, Mochizuki N, Itoh H, Suda T, Oike Y. Tabata M, et al. Among authors: tsukano h. Cell Metab. 2009 Sep;10(3):178-88. doi: 10.1016/j.cmet.2009.08.003. Cell Metab. 2009. PMID: 19723494 Free article.