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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2003 2
2004 2
2005 2
2007 6
2008 4
2009 3
2010 8
2011 9
2012 15
2013 19
2014 20
2015 17
2016 11
2017 19
2018 14
2019 11
2020 14
2021 7
2022 6
2023 7
2024 2

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172 results

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Page 1
Identification of SARS-CoV-2 Mpro inhibitors containing P1' 4-fluorobenzothiazole moiety highly active against SARS-CoV-2.
Higashi-Kuwata N, Tsuji K, Hayashi H, Bulut H, Kiso M, Imai M, Ogata-Aoki H, Ishii T, Kobayakawa T, Nakano K, Takamune N, Kishimoto N, Hattori SI, Das D, Uemura Y, Shimizu Y, Aoki M, Hasegawa K, Suzuki S, Nishiyama A, Saruwatari J, Shimizu Y, Sukenaga Y, Takamatsu Y, Tsuchiya K, Maeda K, Yoshimura K, Iida S, Ozono S, Suzuki T, Okamura T, Misumi S, Kawaoka Y, Tamamura H, Mitsuya H. Higashi-Kuwata N, et al. Among authors: hayashi h. Nat Commun. 2023 Feb 25;14(1):1076. doi: 10.1038/s41467-023-36729-0. Nat Commun. 2023. PMID: 36841831 Free PMC article.
GRL-142 binds to and impairs HIV-1 integrase nuclear localization signal and potently suppresses highly INSTI-resistant HIV-1 variants.
Aoki M, Aoki-Ogata H, Bulut H, Hayashi H, Takamune N, Kishimoto N, Tanaka H, Higashi-Kuwata N, Hattori SI, Das D, Venkateswara Rao K, Iwama K, Davis DA, Hasegawa K, Murayama K, Yarchoan R, Ghosh AK, Pau AK, Machida S, Misumi S, Mitsuya H. Aoki M, et al. Among authors: hayashi h. Sci Adv. 2023 Jul 14;9(28):eadg2955. doi: 10.1126/sciadv.adg2955. Epub 2023 Jul 12. Sci Adv. 2023. PMID: 37436982 Free PMC article.
Do proton pump inhibitors protect against cancer progression in GERD?
Miyashita T, Shah FA, Harmon JW, Marti GP, Matsui D, Okamoto K, Makino I, Hayashi H, Oyama K, Nakagawara H, Tajima H, Fujita H, Takamura H, Murakami M, Ninomiya I, Kitagawa H, Fushida S, Fujimura T, Ohta T. Miyashita T, et al. Among authors: hayashi h. Surg Today. 2013 Aug;43(8):831-7. doi: 10.1007/s00595-012-0395-2. Epub 2012 Oct 31. Surg Today. 2013. PMID: 23111465 Review.
Potent and biostable inhibitors of the main protease of SARS-CoV-2.
Tsuji K, Ishii T, Kobayakawa T, Higashi-Kuwata N, Azuma C, Nakayama M, Onishi T, Nakano H, Wada N, Hori M, Shinohara K, Miura Y, Kawada T, Hayashi H, Hattori SI, Bulut H, Das D, Takamune N, Kishimoto N, Saruwatari J, Okamura T, Nakano K, Misumi S, Mitsuya H, Tamamura H. Tsuji K, et al. Among authors: hayashi h. iScience. 2022 Nov 18;25(11):105365. doi: 10.1016/j.isci.2022.105365. Epub 2022 Nov 1. iScience. 2022. PMID: 36338434 Free PMC article.
Serine hydroxymethyltransferase as a potential target of antibacterial agents acting synergistically with one-carbon metabolism-related inhibitors.
Makino Y, Oe C, Iwama K, Suzuki S, Nishiyama A, Hasegawa K, Okuda H, Hirata K, Ueno M, Kawaji K, Sasano M, Usui E, Hosaka T, Yabuki Y, Shirouzu M, Katsumi M, Murayama K, Hayashi H, Kodama EN. Makino Y, et al. Among authors: hayashi h. Commun Biol. 2022 Jun 23;5(1):619. doi: 10.1038/s42003-022-03555-x. Commun Biol. 2022. PMID: 35739195 Free PMC article.
Analysis of perioperative glucose metabolism using an artificial pancreas.
Okazaki M, Hayashi H, Gabata R, Ohbatake Y, Shinbashi H, Nakanuma S, Makino I, Tajima H, Takamura H, Ohta T. Okazaki M, et al. Among authors: hayashi h. Artif Organs. 2021 Sep;45(9):998-1005. doi: 10.1111/aor.13962. Epub 2021 May 16. Artif Organs. 2021. PMID: 33819346
National survey of hepatobiliary and pancreatic surgery in hemophilia patients in Japan.
Yoshimoto-Haramura T, Hidaka M, Hasegawa K, Suzumura K, Takemura N, Hama N, Mizuno T, Nomi T, Kobayashi T, Sano K, Yokomizo H, Nitta H, Kurata M, Hasegawa Y, Nagayama M, Tani M, Fukumoto T, Ohta M, Hayashi H, Taniguchi H, Ishino S, Aihara T, Murase T, Tsuchida A, Shimamura T, Marubashi S, Kaneko J, Hara T, Matsushima H, Soyama A, Endo T, Eguchi S. Yoshimoto-Haramura T, et al. Among authors: hayashi h. J Hepatobiliary Pancreat Sci. 2022 Mar;29(3):385-393. doi: 10.1002/jhbp.1073. Epub 2021 Nov 17. J Hepatobiliary Pancreat Sci. 2022. PMID: 34726831
172 results