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Evidence suggesting that deletion of expression of N-glycolylneuraminic acid (Neu5Gc) in the organ-source pig is associated with increased antibody-mediated rejection of kidney transplants in baboons.
Iwase H, Jagdale A, Yamamoto T, Bikhet MH, Nguyen HQ, Ezzelarab M, Ayares D, Anderson DJ, Eckhoff DE, Foote JB, Fatima H, Schuurman HJ, Hara H, Cooper DKC. Iwase H, et al. Among authors: schuurman hj. Xenotransplantation. 2021 Jul;28(4):e12700. doi: 10.1111/xen.12700. Epub 2021 May 25. Xenotransplantation. 2021. PMID: 34036638
Life-supporting Kidney Xenotransplantation From Genetically Engineered Pigs in Baboons: A Comparison of Two Immunosuppressive Regimens.
Yamamoto T, Hara H, Foote J, Wang L, Li Q, Klein EC, Schuurman HJ, Zhou H, Li J, Tector AJ, Zhang Z, Ezzelarab M, Lovingood R, Ayares D, Eckhoff DE, Cooper DKC, Iwase H. Yamamoto T, et al. Among authors: schuurman hj. Transplantation. 2019 Oct;103(10):2090-2104. doi: 10.1097/TP.0000000000002796. Transplantation. 2019. PMID: 31283686