In this paper, we present a system that allows patients who require anticoagulation medicine an opportunity to independently manage their dosage concentration with the help of two machine learning algorithms. The basic idea is to predict the next dosage by using a neuronal network and the model predictive control approach, both based on the history of data already available from patients. This machine learning system is expanded by an smartphone application for the patients, and a website for the doctors to support their patients.
Keywords: INR self management; anticoagulation therapy; artificial neural network; computer aided dosage; model predictive control; telemedicine.